Pair of chiral 2D silver(i) enantiomers: chiral recognition of l- and d-histidine via differential pulse voltammetry

Self-assembly of AgPF6 with a pair of chiral tridentate ligands (1S,1 ' S,1 '' S,2R,2 ' R,2 '' R) and (1R,1 ' R,1 '' R,2S,2 ' S,2 '' S)-(benzenetricarbonyltris(azanediyl))tris(2,3-dihydro-1H-indene-2,1-diyl)triisonicotinate (s,r-L) and (r,s-L) in a mixture of methanol and dioxane yields 2D sheets consisting of [Ag(s,r-L)](PF6)center dot 3C(4)H(8)O(2)center dot 0.5H(2)O and [Ag(r,s-L)](PF6)center dot 3C(4)H(8)O(2)center dot 0.5H(2)O, respectively. The differential pulse voltammetric (DPV) technique using the pair of chiral 2D-sheet enantiomers was employed for chiral discrimination of amino acid enantiomers, and was found to be an effective tool for enantio-recognition of l- and d-histidines. Both the size and the binding site of amino acids were strongly dependent on electrochemical enantio-recognition via the chiral 2D sheets.

Automated summary

This study synthesized a pair of chiral 2D sheets through self-assembly and used the differential pulse voltammetric (DPV) technique for chiral discrimination of amino acid enantiomers. It was found to be an effective tool for enantio-recognition.