4.6 Article

Cationic conjugated polymer-based FRET aptasensor for label-free and ultrasensitive ractopamine detection

Journal

RSC ADVANCES
Volume 12, Issue 18, Pages 10911-10914

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d2ra00574c

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Funding

  1. National Natural Science Foundation of China (NSFC) [22134005]
  2. Chongqing Talents Program for Outstanding Scientists [cstc2021ycjhbgzxm0178]

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A label-free fluorescence resonance energy transfer (FRET) platform based on cationic conjugated polymers and aptamers was developed for ultrasensitive and specific ractopamine detection. The method exhibited a wide linear range from 0.05 to 500 μM and a low limit of detection of 47 nM, making it an attractive assay platform for foodborne doping.
A label-free fluorescence resonance energy transfer (FRET) platform based on cationic conjugated polymers and aptamers for ultrasensitive and specific ractopamine detection was constructed. This method exhibited a wide linear range from 0.05 to 500 mu M and a low limit of detection of 47 nM, which make it an attractive assay platform for foodborne doping.

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