Journal
MAKARA JOURNAL OF SCIENCE
Volume 26, Issue 1, Pages 11-24Publisher
UNIV INDONESIA
DOI: 10.7454/mss.v26i1.1271
Keywords
biomaterials; films; gellan gum; hydrogels; wound dressing
Categories
Funding
- Ministry of Higher Education Malaysia [FRGS/1/2018/STG07/UMT/02/11]
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This review discusses the use of gellan gum (GG) as a wound dressing material and explains the effects of various fillers on GG biocomposites.
Gellan gum (GG) has gained considerable attention in the food, chemical, and pharmaceutical industries due to its functional characteristics. It has versatile properties, such as water solubility, easy bio-fabrication, good film/hydrogel-formation, biodegradability, and biocompatibility. These properties render GG a promising material in biomedical applications, specifically in the development of wound dressing materials. In this review, the use of GG biopolymer as a wound dressing material was discussed. Various fillers, such as titanium dioxides, clay, drug, and honey, have been incorporated in GG to produce film, hydrogel, or scaffold materials. The effects of filler on the mechanical performance, physical properties, antibacterial activities, and healing activities of GG biocomposites were explained. Overall, this review summarizes the effect of fillers on GG biocomposites for various biomedical uses.
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