Journal
CURRENT OPINION IN BIOMEDICAL ENGINEERING
Volume 21, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.cobme.2021.100367
Keywords
Antibacterial; Coating; Electrophoretic deposition; Bacteriocidic
Categories
Funding
- DFG (Deutsche Forschungsge-meinschaft, Germany) [BO 1191/25-1]
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Electrophoretic deposition (EPD) is an effective coating technology that imparts antibacterial properties to medical implants without altering the material's properties. This review paper summarizes novel strategies using EPD to prevent bacterial infections, based on relevant studies from the past two years, and critically reflects on the future prospects of EPD-based biomedical coatings.
Bacterial infections are one of the leading causes for long-term failure of medical implants, associated with hospitalization, costly revision surgeries, increased morbidity and even mortality. Electrophoretic deposition (EPD) appears as a suitable coating technology to confer antibacterial efficacy to implant surfaces without changing the properties of the constituent (or base) material. Typical antibacterial coatings by EPD rely on bactericidal (release-killing, contact-killing and stimuli responsive-killing) and bacteriostatic (anti-adhesive) approaches. The current review paper presents novel strategies to prevent bacterial infections by means of EPD focusing on relevant published studies in the last two years and provides a critical reflection on future prospects of EPD-based biomedical coatings.
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