Journal
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
Volume 35, Issue 4, Pages 645-665Publisher
SPRINGER
DOI: 10.1007/s10334-022-01011-9
Keywords
Prostate cancer; Proton magnetic resonance spectroscopy; State-of-the-art review; Spectroscopic imaging
Funding
- European Union [813120]
- Marie Curie Actions (MSCA) [813120] Funding Source: Marie Curie Actions (MSCA)
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This paper reviews the developments of H-1-MR spectroscopic imaging methods in investigating prostate cancer, highlighting recent advancements and future developments to overcome challenges in clinical applications.
In this paper, we review the developments of H-1-MR spectroscopic imaging (MRSI) methods designed to investigate prostate cancer, covering key aspects such as specific hardware, dedicated pulse sequences for data acquisition and data processing and quantification techniques. Emphasis is given to recent advancements in MRSI methodologies, as well as future developments, which can lead to overcome difficulties associated with commonly employed MRSI approaches applied in clinical routine. This includes the replacement of standard PRESS sequences for volume selection, which we identified as inadequate for clinical applications, by sLASER sequences and implementation of H-1 MRSI without water signal suppression. These may enable a new evaluation of the complementary role and significance of MRSI in prostate cancer management.
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