4.6 Article

Visible-light-induced cyclization of cyclic N-sulfonyl ketimines to N-sulfonamide fused imidazolidines

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 20, Issue 18, Pages 3798-3802

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d2ob00460g

Keywords

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Funding

  1. National Natural Science Foundation of China [21971224, 22071222, 22171249]
  2. Key Research Projects of Universities in Henan Province [21A150053]
  3. Natural Science Foundation of Henan Province [202300410375]

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A visible-light-induced metal-free cascade cyclization was developed for the synthesis of N-sulfonamide-fused imidazolidines. The reaction used 3 mol% of eosin Y as the photocatalyst at room temperature under visible light irradiation, resulting in good yields of the desired products (32 examples, up to 86% yields).
A visible-light-induced metal-free cascade cyclization of cyclic N-sulfonyl ketimines with N-arylglycines for the construction of N-sulfonamide-fused imidazolidines was developed. The procedure employed 3 mol% of eosin Y as the photocatalyst at room temperature under visible light irradiation, providing various N-sulfonamide-fused imidazolidines in good yields (32 examples, up to 86% yields).

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