4.6 Review

Application of smart multifunctional nanoprobes in tumor diagnosis and treatment

Journal

JOURNAL OF MATERIALS CHEMISTRY B
Volume 10, Issue 19, Pages 3601-3613

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d2tb00326k

Keywords

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Funding

  1. National Natural Science Foundation of China [82001894/21776044/21606041/21503035]
  2. Joint Research Fund Liaoning-Shenyang National Laboratory for Materials Science [2019JH3/30100011]

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Nanotechnology has provided new tools for cancer treatment, particularly with the development of smart multifunctional nanoprobes. Off-On nanoprobes and Charge-Reversal nanoprobes have been the focus of research and offer potential for early diagnosis and treatment of cancer.
Cancer is one of the major diseases that pose a threat to human health and life, especially because it is difficult to diagnose and cure, and recurs easily. In recent years, the development of nanotechnology has provided researchers with new tools for cancer treatment. In particular, nanoprobes that facilitate integrated diagnosis and treatment, high-resolution imaging, and accurate tumor targeting provide new avenues for the early detection and treatment of cancer. This review focuses on the preparations and applications of two kinds of smart multifunctional nanoprobes: Off-On nanoprobes and Charge-Reversal nanoprobes. This review also briefly discusses their mechanisms of action, as they could provide new ideas for the further development of this field.

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