Journal
ANALYST
Volume 147, Issue 11, Pages 2338-2354Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2an00349j
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Funding
- National Natural Science Foundation of China [21705084]
- Natural Science Foundation of Shandong Province of China [ZR2017BB074]
- National Training Program of Innovation and Entrepreneurship for Undergraduates [S202010431027]
- Qilu University of Technology of Training Program of Innovation and Entrepreneurship for Undergraduates [xj201910431125]
- Research Leader Workshop of Jinan [2021GXRC101]
- Key Research and Development Program of Shandong Province [2021CXGC010808]
- Innovation Team of Jinan City [2018GXRC004]
- Special Funds for Taishan Scholars Project
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This review provides a brief introduction to the phenomenon, principle, and applications of aggregation-induced emission (AIE) and aggregation-induced electrochemiluminescence (AIECL) emitters. It focuses on the applications of AIECL sensors in bioanalytical detection and proposes future prospects and challenges for AIECL sensors.
In recent years, with the rapid development of electrochemiluminescence (ECL) sensors, more luminophores have been designed to achieve high-throughput and reliable analysis. Impressively, after the proposed fantastic concept of aggregation-induced electrochemiluminescence (AIECL) by Cola, the application of AIECL emitters provides more abundant choices for the further improvement of ECL sensors. In this review, we briefly report the phenomenon, principle and representative applications of aggregation-induced emission (AIE) and AIECL emitters. Moreover, it is noteworthy that the cases of AIECL sensors for bioanalytical detection are summarized in detail, from 2017 to now. Finally, inspired by the applications of AIECL emitters, relevant prospects and challenges for AIECL sensors are proposed, which is of great significance for exploring more advanced bioanalytical detection technology.
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