Journal
LAB ON A CHIP
Volume 22, Issue 12, Pages 2237-2258Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2lc00169a
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Funding
- TuBTAK (The Scientific and Technological Research Council of Turkey) Support Program for Scientific and Technological Research Project [221M243, 118S040]
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Thanks to the development of microfluidics, researchers are able to control and monitor the cavitation phenomenon in micro-scale, providing suitable platforms for energy utilization in bio-related and industrial applications. However, the behavior of cavitation bubbles in micro-scale differs from macro-scale, necessitating in-depth investigations and application of micro-scale cavitation.
Thanks to the developments in the area of microfluidics, the cavitation-on-a-chip concept enabled researchers to control and closely monitor the cavitation phenomenon in micro-scale. In contrast to conventional scale, where cavitation bubbles are hard to be steered and manipulated, lab-on-a-chip devices provide suitable platforms to conduct smart experiments and design reliable devices to carefully harness the collapse energy of cavitation bubbles in different bio-related and industrial applications. However, bubble behavior deviates to some extent when confined to micro-scale geometries in comparison to macro-scale. Therefore, fundamentals of micro-scale cavitation deserve in-depth investigations. In this review, first we discussed the physics and fundamentals of cavitation induced by tension-based as well as energy deposition-based methods within microfluidic devices and discussed the similarities and differences in micro and macro-scale cavitation. We then covered and discussed recent developments in bio-related applications of micro-scale cavitation chips. Lastly, current challenges and future research directions towards the implementation of micro-scale cavitation phenomenon to emerging applications are presented.
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