4.5 Article

Risk of Lung Cancer and Occupational Exposure to Polycyclic Aromatic Hydrocarbons Among Workers Cohorts - Worldwide, 1969-2022

Journal

CHINA CDC WEEKLY
Volume 4, Issue 17, Pages 364-+

Publisher

Chinese Center for Disease Control and Prevention
DOI: 10.46234/ccdcw2022.085

Keywords

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Funding

  1. National Natural Science Foundation of China [81971416, 82073525]
  2. Beijing Natural Science Foundation [7214279]

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This report analyzes cancer cases from PAHs-exposed workers in China and other countries, calculates the risk of lung cancer, and confirms the increased risk in certain occupations. The findings highlight the importance of preventing lung cancer in various occupations and establishing guidelines for monitoring and promoting health in related working environments.
What is already known about this topic? Lung cancer has a high mortality, resulting in a severe disease burden. Polycyclic aromatic hydrocarbons (PAHs) are definitive carcinogen to human, and occupational exposure to PAHs is associated with lung cancer. What is added by this report? We analyzed the cancer cases from cohort studies on various PAHs exposed workers in China and other countries, calculated the quantitative risk of lung cancer based on meta-analyses, and confirmed the increased risk from lung cancer in selected PAHs exposed occupations. What are the implications for public health practices? There is a clear need to prevent lung cancer on a wide range of PAHs-related occupations in China and around the world. It is crucial to establish guidelines for improving the monitoring on exposure and health promotion in related working environments.

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