4.5 Review

Fe-Catalyzed Cross-Dehydrogenative Coupling Reactions

Journal

TOPICS IN CURRENT CHEMISTRY
Volume 374, Issue 4, Pages -

Publisher

SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1007/s41061-016-0038-y

Keywords

Cross-dehydrogenative coupling (CDC); Iron catalysis; C-H bond; C-C bond; C-X bond

Funding

  1. National Science Foundation of China
  2. State Key Laboratory of Heavy Oil Processing
  3. Fundamental Research Funds for the Central Universities
  4. Research Funds of Renmin University of China
  5. Beijing National Laboratory for Molecular Sciences

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Cross-dehydrogenative coupling (CDC), which enables the formation of carbon-carbon (C-C) and C-heteroatom bonds from the direct coupling of two C-H bonds or C-H/X-H bonds, represents a new state of the art in the field of organic chemistry. Iron, a prominent metal, has already shown its versatile application in chemical synthesis. This review attempts to provide a comprehensive understanding of the evolution of cross-dehydrogenative coupling via iron catalysis, as well as its application in synthetic chemistry.

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