4.2 Article

Right ventricular strain and volume analyses through deep learning-based fully automatic segmentation based on radial long-axis reconstruction of short-axis cine magnetic resonance images

Journal

Publisher

SPRINGER
DOI: 10.1007/s10334-022-01017-3

Keywords

Right ventricle; Myocardial remodeling; Pulmonary hypertension; Cine magnetic resonance imaging; Myocardial segmentation; Deep learning

Funding

  1. Center for Clinical and Translational Research of Kyushu University Hospital
  2. JSPS KAKENHI [JP20K16729]

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In this study, a deep learning-based fully automatic RV segmentation technique targeting RLA images showed higher accuracy compared to conventional SA methods in terms of RV strain parameter measurements. The proposed RLA method achieved accurate full automatic extraction of the entire RV region from available CMR cine images without additional imaging, overcoming limitations in RV visualization in echocardiography.
Objective We propose a deep learning-based fully automatic right ventricle (RV) segmentation technique that targets radially reconstructed long-axis (RLA) images of the center of the RV region in routine short axis (SA) cardiovascular magnetic resonance (CMR) images. Accordingly, the purpose of this study is to compare the accuracy of deep learning-based fully automatic segmentation of RLA images with the accuracy of conventional deep learning-based segmentation in SA orientation in terms of the measurements of RV strain parameters. Materials and methods We compared the accuracies of the above-mentioned methods in RV segmentations and in measuring RV strain parameters by Dice similarity coefficients (DSCs) and correlation coefficients. Results DSC of RV segmentation of the RLA method exhibited a higher value than those of the conventional SA methods (0.84 vs. 0.61). Correlation coefficient with respect to manual RV strain measurements in the fully automatic RLA were superior to those in SA measurements (0.5-0.7 vs. 0.1-0.2). Discussion Our proposed RLA realizes accurate fully automatic extraction of the entire RV region from an available CMR cine image without any additional imaging. Our findings overcome the complexity of image analysis in CMR without the limitations of the RV visualization in echocardiography.

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