Journal
RESPIRATORY CARE
Volume 67, Issue 5, Pages 594-606Publisher
DAEDALUS ENTERPRISES INC
DOI: 10.4187/respcare.09489
Keywords
patent ductus arteriosus; prematurity; surgical ligation; transcatheter PDA closure; transport; anesthesia; cardiorespiratory instability; post-ligation cardiac syndrome; high-frequency ventilation
Categories
Ask authors/readers for more resources
This review summarizes the pathophysiologic manifestations, treatment options, and management of hemodynamically significant PDA in preterm infants. Additionally, the available literature surrounding the respiratory support and outcomes of preterm infants following definitive PDA closure is reviewed.
A persistent patent ductus arteriosus (PDA) can have significant clinical consequences in preterm infants, depending on the degree of left-to-right shunting, its impact on cardiac performance, and associated perinatal risk factors that can mitigate or exacerbate the shunt. Although the best management strategy remains contentious, PDAs that have contraindications to, or have failed medical management have historically undergone surgical ligation. Recently smaller occluder devices and delivery systems have allowed for minimally invasive closure in the catheterization laboratory even in extremely premature infants. The present review summarizes the pathophysiologic manifestations, treatment options and management of hemodynamically significant PDA in preterm infants. Additionally, we review the available literature surrounding the respiratory support and outcomes of preterm infants following definitive PDA closure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available