Journal
BIOENGINEERING-BASEL
Volume 9, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/bioengineering9050187
Keywords
bioreactor; tissue engineering; automation; sensor
Funding
- TSRI [71717]
Ask authors/readers for more resources
This paper presents the development of a programmable bioreactor and a novel pH sensor, and demonstrates their potential applications in cell culture.
Tissue engineering technology has been advanced and applied to various applications in the past few years. The presence of a bioreactor is one key factor to the successful development of advanced tissue engineering products. In this work, we developed a programmable bioreactor with a controlling program that allowed each component to be automatically operated. Moreover, we developed a new pH sensor for non-contact and real-time pH monitoring. We demonstrated that the prototype bioreactor could facilitate automatic cell culture of L929 cells. It showed that the cell viability was greater than 80% and cell proliferation was enhanced compared to that of the control obtained by a conventional cell culture procedure. This result suggests the possibility of a system that could be potentially useful for medical and industrial applications, including cultured meat, drug testing, etc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available