Journal
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
Volume 26, Issue 10, Pages 3570-3576Publisher
VERDUCI PUBLISHER
Keywords
Cervical cancer CaSki; SiHa; Hela; Me180; INBL; Human leukocyte antigen
Categories
Funding
- Higher Education Center of Excellence [311/CIP-PM/4401005]
- Universiti Sains Malaysia [1001/CIPPM/813067]
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Cervical cancer is a major cause of death in women worldwide, and extensive research is being conducted to develop efficient diagnostics and treatments. The characterization of cervical cell lines is essential for these studies, as it ensures the suitability of the cells and enables accurate therapy.
Cervical cancer is one of the leading causes of death in women worldwide. Extensive research is ongoing to develop efficient diagnostics and therapeutic approaches for cervical cancer, which rely on the preliminary studies based on cervical cell lines. It is essential to characterize these cell lines to ensure the suitability of the cells for each study. In this review, the human leukocyte antigen (HLA) molecule expressed on each cervical cancer line is presented. HLA characterization of the cervical cancer cell lines is essential to increase the specificity of treatment towards certain type of cervical cancer, allowing accurate therapy. HLA characterization is also important for the generation of novel diagnostics and/or therapeutics molecules, especially for HLA-based strategies.
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