Journal
ANALYST
Volume 147, Issue 13, Pages 3096-3100Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2an00661h
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Funding
- National Natural Science Foundation of China [22074018]
- Quanzhou City Science & Technology Program of China [2019N072S]
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An ECL immunosensor for the detection of carcinoembryonic antigen (CEA) was constructed using oxidized multi-walled carbon nanotube/nano-gold (AuNP-ox-MWCNT) composites with strong electrochemiluminescence (ECL) activity. The immunosensor showed a wide linear response range and a low detection limit, and was simple to fabricate and label-free.
Oxidized multi-walled carbon nanotube/nano-gold (AuNP-ox-MWCNT) composites with strong electrochemiluminescence (ECL) activity were applied to construct a new ECL immunosensor for the detection of carcinoembryonic antigen (CEA). The immunosensor showed a linear response range of 10-100 ng mL(-1) and detection limit of 0.76 ng mL(-1) (at a signal-to-noise ratio of 3). The as-developed immunosensor exhibited several advantages, including being simple to fabricate and being label free. The results indicated that ox-MWCNTs as a luminescent material have great application potential in analysis.
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