4.3 Article

Diagnosing chronic endometritis: when simplification fails to clarify

Related references

Note: Only part of the references are listed.
Review Immunology

Single-cell resolution of plasma cell fate programming in health and disease

Celine Delaloy et al.

Summary: Plasma cells were traditionally seen as a homogeneous population dedicated to antibody secretion, but recent studies have revealed phenotypic and functional heterogeneity in this cell type. Advances in single cell technologies have shed light on the factors influencing the fate and diversity of plasma cells, contributing to a better understanding of their roles in immune responses and diseases.

EUROPEAN JOURNAL OF IMMUNOLOGY (2022)

Article Genetics & Heredity

The role of endometrial staining for CD138 as a marker of chronic endometritis in predicting live birth

N. S. Herlihy et al.

Summary: This study found that endometrial plasma cells are present in half of the general infertile population, but do not predict implantation, clinical pregnancy, clinical pregnancy loss, or live birth rates at low levels.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2022)

Article Obstetrics & Gynecology

Management of recurrent implantation failure: British Fertility Society policy and practice guideline

Mariano Mascarenhas et al.

Summary: Recurrent implantation failure (RIF) is defined as the absence of a positive pregnancy test after three consecutive transfers of good quality embryos. There is significant variation in clinical practices for managing RIF. The British Fertility Society (BFS) guideline analyzes evidence for investigations and therapies used in RIF, providing recommendations for clinical practice and further research to improve understanding and management of RIF.

HUMAN FERTILITY (2022)

Article Medicine, General & Internal

Differential Vaginal Microbiota Profiling in Lactic-Acid-Producing Bacteria between Infertile Women with and without Chronic Endometritis

Suguru E. Tanaka et al.

Summary: This study found that certain bacteria in the vaginal secretions microbiota have significantly lower detection rates and abundance in CE patients compared to non-CE group, suggesting the potential of using vaginal secretions microbiota for predicting CE. This provides a new approach for the diagnosis and prediction of CE using less invasive VS sampling rather than intrauterine interventions.

DIAGNOSTICS (2022)

Article Immunology

Alteration in endometrial helper T-cell subgroups in chronic endometritis

Jun Kitazawa et al.

Summary: Women with chronic endometritis (CE) have altered CD4(+) T-cell profile in their endometrium, with more Th1 cells and fewer Th2 cells compared to non-CE patients. This finding may provide insights into the pathophysiology and treatment of CE.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

Article Immunology

Diagnosis of chronic endometritis: How many CD138+ cells/HPF in endometrial stroma affect pregnancy outcome of infertile women?

Yuye Li et al.

Summary: This study aimed to establish the minimum number of CD138(+) plasma cells for identifying clinically relevant chronic endometritis (CE). Results showed that a high number of CD138(+) cells were associated with decreased pregnancy outcomes. Immunohistochemical analysis of CD138(+) cells can reliably detect CE, with >= 5 plasma cells in at least one out of 30 HPF being a key indicator.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

Article Obstetrics & Gynecology

The Diagnostic Criteria for Chronic Endometritis: A Survey of Pathologists

Samantha L. Margulies et al.

Summary: Chronic endometritis lacks a clear definition compared to acute endometritis, leading to variability among pathologists in diagnosing and managing the disease. Standardization of diagnostic criteria is essential to ensure proper management of patients with chronic endometritis.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY (2021)

Article Obstetrics & Gynecology

Multiple endometrial polyps is associated with higher risk of chronic endometritis in reproductive-aged women

Luyan Guo et al.

Summary: The study found a significant positive association between multiple EP and CE, while there was no clear relationship between single EP and CE. Multivariable analysis showed that abnormal uterine bleeding (AUB) and multiple EP were independently associated with CE, while single EP did not increase the odds of CE compared to the non-polyp group.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (2021)

Review Obstetrics & Gynecology

Clinical practice guidelines for recurrent miscarriage in high-income countries: a systematic review

Marita Hennessy et al.

Summary: A systematic review was conducted to identify clinical practice guidelines for recurrent miscarriage within high-income countries published since 2000. Most guidelines scored poorly in terms of applicability and editorial independence, with varying levels of consensus and some conflicting recommendations between guidelines.

REPRODUCTIVE BIOMEDICINE ONLINE (2021)

Article Immunology

Interaction Between Chronic Endometritis Caused Endometrial Microbiota Disorder and Endometrial Immune Environment Change in Recurrent Implantation Failure

Peigen Chen et al.

Summary: Investigating the interaction between chronic endometritis (CE) induced endometrial microbiota disorder and endometrial immune environment change in recurrent implantation failure (RIF), it was found that CD4 T cells and macrophages exhibited significant differences in abundance between CE and non-CE patients. The endometrial microorganisms in CE patients, particularly Phyllobacterium and Sphingomonas, played a role in regulating immune cells by interfering with carbohydrate and/or fat metabolism. The microbial disorders in CE endometrium led to increased synthesis of lipopolysaccharide, potentially affecting Th17 and Th1/Th17 ratio.

FRONTIERS IN IMMUNOLOGY (2021)

Article Obstetrics & Gynecology

Hysteroscopic detection of chronic endometritis: Evaluating proposed hysteroscopic features suggestive of chronic endometritis

Orestis Tsonis et al.

Summary: The study aimed to evaluate the effectiveness of hysteroscopic features in diagnosing chronic endometritis (CE), with micropolyposis, stromal oedema, focal or diffuse hyperaemia, and strawberry aspect showing higher diagnostic accuracy. Endometrial polyps are not valid hysteroscopic features in suspected cases of CE.

JOURNAL OF GYNECOLOGY OBSTETRICS AND HUMAN REPRODUCTION (2021)

Review Immunology

Know your enemy or find your friend?-Induction of IgA at mucosal surfaces*

Mats Bemark et al.

Summary: Most antibodies in the body are IgA class, primarily produced by plasma cells in the lamina propria of the gastrointestinal tract and found in various organs. These antibodies play a crucial role in maintaining a healthy balance between the host and bacteria, as well as neutralizing pathogens.

IMMUNOLOGICAL REVIEWS (2021)

Review Obstetrics & Gynecology

Hysteroscopic findings in chronic endometritis

Antonio LA Marca et al.

Summary: Chronic endometritis is a subtle and underdiagnosed condition that can cause infertility, with histological examination and hysteroscopy being the main diagnostic tools. Though hysteroscopy shows high sensitivity, further studies are needed to determine the most reliable diagnostic technique.

MINERVA OBSTETRICS AND GYNECOLOGY (2021)

Review Immunology

Harmful and beneficial effects of inflammatory response on reproduction: sterile and pathogen-associated inflammation

Yasuyuki Negishi et al.

Summary: Inflammation plays a crucial role in pregnancy complications, being triggered by both microbial and non-microbial causes. Immune cells and inflammatory mediators are involved in abnormal inflammation, while appropriate inflammation is necessary for successful pregnancy outcomes. Understanding the relationship between pregnancy and inflammation may provide new perspectives on normal pregnancy progress and treatment strategies for pregnancy complications.

IMMUNOLOGICAL MEDICINE (2021)

Review Genetics & Heredity

Chronic endometritis and altered embryo implantation: a unified pathophysiological theory from a literature systematic review

Giovanni Buzzaccarini et al.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2020)

Article Immunology

Impact of chronic endometritis on endometrial receptivity analysis results and pregnancy outcomes

Keiji Kuroda et al.

IMMUNITY INFLAMMATION AND DISEASE (2020)

Article Obstetrics & Gynecology

Chronic Endometritis, a Common Disease Hidden Behind Endometrial Polyps in Premenopausal Women: First Evidence From a Case-Control Study

Ettore Cicinelli et al.

JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY (2019)

Article Immunology

Plasma Cells, the Next Generation: Beyond Antibody Secretion

Peter D. Pioli

FRONTIERS IN IMMUNOLOGY (2019)

Article Endocrinology & Metabolism

Endometrial TGF-β, IL-10, IL-17 and autophagy are dysregulated in women with recurrent implantation failure with chronic endometritis

Wen-juan Wang et al.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2019)

Editorial Material Obstetrics & Gynecology

Chronic endometritis and the plasma cell, fact versus fiction

John V. Groth

FERTILITY AND STERILITY (2018)

Review Obstetrics & Gynecology

Endometritis: new time, new concepts

Kotaro Kitaya et al.

FERTILITY AND STERILITY (2018)

Article Obstetrics & Gynecology

How uterine microbiota might be responsible for a receptive, fertile endometrium

Marilen Benner et al.

HUMAN REPRODUCTION UPDATE (2018)

Letter Obstetrics & Gynecology

Scoring of mosaic embryos after preimplantation genetic testing: a rollercoaster ride between fear, hope and embryo wastage

Maximilian Murtinger et al.

REPRODUCTIVE BIOMEDICINE ONLINE (2018)

Letter Obstetrics & Gynecology

How PGS/PGT-A laboratories succeeded in losing all credibility

Norbert Gleicher et al.

REPRODUCTIVE BIOMEDICINE ONLINE (2018)

Review Medicine, General & Internal

Overdiagnosis in primary care: framing the problem and finding solutions

Minal S. Kale et al.

BMJ-BRITISH MEDICAL JOURNAL (2018)

Article Multidisciplinary Sciences

Single-cell reconstruction of the early maternal-fetal interface in humans

Roser Vento-Tormo et al.

NATURE (2018)

Article Public, Environmental & Occupational Health

Efficient treatment of chronic endometritis through a novel approach of intrauterine antibiotic infusion: a case series

Konstantinos Sfakianoudis et al.

BMC WOMENS HEALTH (2018)

Article Endocrinology & Metabolism

Chronic endometritis modifies decidualization in human endometrial stromal cells

Di Wu et al.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2017)

Review Cell Biology

The inflammation paradox in the evolution of mammalian pregnancy: turning a foe into a friend

Arun Rajendra Chavan et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2017)

Article Obstetrics & Gynecology

Pregnancy outcomes in women with chronic endometritis and recurrent pregnancy loss

Dana B. McQueen et al.

FERTILITY AND STERILITY (2015)

Article Multidisciplinary Sciences

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

Shabnam Shalapour et al.

NATURE (2015)

Article Obstetrics & Gynecology

Hysteroscopy in women with abnormal uterine bleeding: a meta-analysis on four major endometrial pathologies

Fani Gkrozou et al.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2015)

Article Immunology

Immunoglobulin A as an anti- inflammatory agent

R. C. Monteiro

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2014)

Article Obstetrics & Gynecology

Chronic endometritis in women with recurrent early pregnancy loss and/or fetal demise

Dana B. McQueen et al.

FERTILITY AND STERILITY (2014)

Letter Medicine, General & Internal

The Cost of Defensive Medicine on 3 Hospital Medicine Services

Michael B. Rothberg et al.

JAMA INTERNAL MEDICINE (2014)

Editorial Material Medicine, General & Internal

Ignaz Phillip Semmelweis' studies of death in childbirth

Irvine Loudon

JOURNAL OF THE ROYAL SOCIETY OF MEDICINE (2013)

Editorial Material Medicine, General & Internal

Preventing overdiagnosis: how to stop harming the healthy

Ray Moynihan et al.

BMJ-BRITISH MEDICAL JOURNAL (2012)

Article Obstetrics & Gynecology

The value of hysteroscopy in diagnosis of chronic endometritis in patients with unexplained recurrent spontaneous abortion

Jaleh Zolghadri et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2011)

Editorial Material Obstetrics & Gynecology

Prevalence of chronic endometritis in recurrent miscarriages

Kotaro Kitaya

FERTILITY AND STERILITY (2011)

Article Obstetrics & Gynecology

Chronic endometritis is a frequent finding in women with recurrent implantation failure after in vitro fertilization

Erika B. Johnston-MacAnanny et al.

FERTILITY AND STERILITY (2010)

Article Obstetrics & Gynecology

Detection of chronic endometritis at fluid hysteroscopy

E Cicinelli et al.

JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY (2005)

Article Obstetrics & Gynecology

Endometrial micropolyps at fluid hysteroscopy suggest the existence of chronic endometritis

E Cicinelli et al.

HUMAN REPRODUCTION (2005)

Article Infectious Diseases

Endometrial plasma cells: Do they indicate subclinical pelvic inflammatory disease?

SL Achilles et al.

SEXUALLY TRANSMITTED DISEASES (2005)

Article Immunology

Human decidual natural killer cells are a unique NK cell subset with immunomodulatory potential

LA Koopman et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2003)

Article Obstetrics & Gynecology

Detection of chronic endometritis by diagnostic hysteroscopy in asymptomatic infertile patients

F Polisseni et al.

GYNECOLOGIC AND OBSTETRIC INVESTIGATION (2003)