Synthesis and characterization of peptidomimetics containing oxazolidin-2-one and oxazolidine scaffolds

In this paper, we report the synthesis of peptidomimetics containing oxazolidin-2-one and oxazolidine rings. The two of these heterocyclic peptidomimetics novel series were obtained from serine as starting material through an efficient intramolecular cyclization. In the case of oxazolidine, the formation of only one diastereoisomer was observed.

Automated summary

In this paper, the synthesis of peptidomimetics containing oxazolidin-2-one and oxazolidine rings is reported. Two novel series of these heterocyclic peptidomimetics were obtained through an efficient intramolecular cyclization using serine as the starting material. In the case of oxazolidine, the formation of only one diastereoisomer was observed.