☆ 3.8 Review

Recent Advances in Influenza, HIV and SARS-CoV-2 Infection Prevention and Drug Treatment-The Need for Precision Medicine

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FRONTIERS IN MICROBIOLOGY (2020)

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Computational Drug Repositioning: Current Progress and Challenges

Younhee Ko

APPLIED SCIENCES-BASEL (2020)

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Editorial: In silico Methods for Drug Design and Discovery

Simone Brogi et al.

FRONTIERS IN CHEMISTRY (2020)

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Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen

Fatemeh Heidary et al.

JOURNAL OF ANTIBIOTICS (2020)

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Article Cell Biology

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice

Athri D. Rathnayake et al.

SCIENCE TRANSLATIONAL MEDICINE (2020)

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A painful lesson from the COVID-19 pandemic: the need for broad-spectrum, host-directed antivirals

Vipul C. Chitalia et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2020)

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News Item Multidisciplinary Sciences

MAKING SENSE OF CORONAVIRUS MUTATIONS

Ewen Callaway

NATURE (2020)

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EMBRACE OF UNPROVEN COVID TREATMENT HINDERS DRUG TRIALS

Emiliano Rodriguez Mega

NATURE (2020)

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Article Virology

HLA-associated protection of lymphocytes during influenza virus infection

Eliana E. Ochoa et al.

VIROLOGY JOURNAL (2020)

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Review Immunology

Phage Display Derived Monoclonal Antibodies: From Bench to Bedside

Mohamed A. Alfaleh et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Article Pharmacology & Pharmacy

Discovery of HIV entry inhibitors via a hybrid CXCR4 and CCR5 receptor pharmacophore-based virtual screening approach

Muhammad Usman Mirza et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

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Article Virology

Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses

Marianna Tampere et al.

VIRUSES-BASEL (2020)

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Anti-Influenza Strategies Based on Nanoparticle Applications

Klaudia Wieczorek et al.

PATHOGENS (2020)

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Advanced drug delivery systems can assist in managing influenza virus infection: A hypothesis

Yinghan Chan et al.

MEDICAL HYPOTHESES (2020)

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Editorial Material Critical Care Medicine

Precision medicine for COVID-19: a call for better clinical trials

Gentle Sunder Shrestha et al.

CRITICAL CARE (2020)

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Curcumin as an Antiviral Agent

Morgan R. Jennings et al.

VIRUSES-BASEL (2020)

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Recent developments of nanotherapeutics for targeted and long-acting, combination HIV chemotherapy

Yu Gao et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

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A year of terror and a century of reflection: perspectives on the great influenza pandemic of 1918-1919

Michaela E. Nickol et al.

BMC INFECTIOUS DISEASES (2019)

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Article Pharmacology & Pharmacy

Identification of NMS-873, an allosteric and specific p97 inhibitor, as a broad antiviral against both influenza A and B viruses

Jiantao Zhang et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

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CCR5/CXCR4 Dual Antagonism for the Improvement of HIV Infection Therapy

Fedora Grande et al.

MOLECULES (2019)

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Influenza Virus Infections and Cellular Kinases

Robert Meineke et al.

VIRUSES-BASEL (2019)

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What's New with Flu? An Overview

Seema S. Lakdawala et al.

VIRUSES-BASEL (2019)

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Current and Novel Approaches in Influenza Management

Erasmus Kotey et al.

VACCINES (2019)

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Article Chemistry, Medicinal

An Influenza Virus Entry Inhibitor Targets Class II PI3 Kinase and Synergizes with Oseltamivir

Ryan O'Hanlon et al.

ACS INFECTIOUS DISEASES (2019)

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Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures

Andres Pizzorno et al.

FRONTIERS IN IMMUNOLOGY (2019)

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Antiviral Therapy for the Next Influenza Pandemic

Aeron C. Hurt

TROPICAL MEDICINE AND INFECTIOUS DISEASE (2019)

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Drug Repurposing Approaches for the Treatment of Influenza Viral Infection: Reviving Old Drugs to Fight Against a Long-Lived Enemy

Andres Pizzorno et al.

FRONTIERS IN IMMUNOLOGY (2019)

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Repurposing of Kinase Inhibitors as Broad-Spectrum Antiviral Drugs

Stanford Schor et al.

DNA AND CELL BIOLOGY (2018)

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Polypharmacology in HIV inhibition: can a drug with simultaneous action against two relevant targets be an alternative to combination therapy?

Sonia de Castro et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

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Article Pharmacology & Pharmacy

Oseltamivir-zanamivir combination therapy suppresses drug-resistant H1N1 influenza A viruses in the hollow fiber infection model (HFIM) system

Camilly P. Pires de Mello et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2018)

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Article Biochemistry & Molecular Biology

In-depth phylodynamics, evolutionary analysis and in silico predictions of universal epitopes of Influenza A subtypes and Influenza B viruses

Ricardo Duraes-Carvalho et al.

MOLECULAR PHYLOGENETICS AND EVOLUTION (2018)

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Characterization of Nanodiamond-based anti-HIV drug Delivery to the Brain

Upal Roy et al.

SCIENTIFIC REPORTS (2018)

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An Increased Frequency in HLA Class I Alleles and Haplotypes Suggests Genetic Susceptibility to Influenza A (H1N1) 2009 Pandemic: A Case-Control Study

Ramces Falfan-Valencia et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2018)

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Epidemiological characteristics of human-infective RNA viruses

Mark E. J. Woolhouse et al.

SCIENTIFIC DATA (2018)

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Reassessing the Global Mortality Burden of the 1918 Influenza Pandemic

Peter Spreeuwenberg et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2018)

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Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents

Frederick G. Hayden et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

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Neuraminidase Inhibitors in Influenza Treatment and Prevention-Is It Time to Call It a Day?

Cesar Parra-Rojas et al.

VIRUSES-BASEL (2018)

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Economic Impact of HIV in the Highly Active Antiretroviral Therapy Era - Reflections Looking Forward

Juan Oliva-Moreno et al.

AIDS REVIEWS (2018)

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In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit

Takeshi Noshi et al.

ANTIVIRAL RESEARCH (2018)

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A perspective on multi-target drug discovery and design for complex diseases

Rona R. Ramsay et al.

CLINICAL AND TRANSLATIONAL MEDICINE (2018)

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Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial

John H. Beigel et al.

LANCET INFECTIOUS DISEASES (2017)

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Article Oncology

The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma

Ronan Le Moigne et al.

MOLECULAR CANCER THERAPEUTICS (2017)

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Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase

Yousuke Furuta et al.

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2017)

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Article Multidisciplinary Sciences

Structural and regulatory diversity shape HLA-C protein expression levels

Gurman Kaur et al.

NATURE COMMUNICATIONS (2017)

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Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1

Romel D. Mackelprang et al.

PLOS PATHOGENS (2017)

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Advancements in Developing Strategies for Sterilizing and Functional HIV Cures

Wei Xu et al.

BIOMED RESEARCH INTERNATIONAL (2017)

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The genetic background influences the cellular and humoral immune responses to vaccines

M. Zeng et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2016)

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Approved Antiviral Drugs over the Past 50 Years

Erik De Clercq et al.

CLINICAL MICROBIOLOGY REVIEWS (2016)

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One size does not fit all: Challenging some dogmas and taboos in drug discovery

Christina L. L. Chai et al.

FUTURE MEDICINAL CHEMISTRY (2016)

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Phage display-derived human antibodies in clinical development and therapy

Andre Frenzel et al.

MABS (2016)

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Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

Travis K. Warren et al.

NATURE (2016)

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Aging of the Immune System Mechanisms and Therapeutic Targets

Cornelia M. Weyand et al.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2016)

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Repurposing Kinase Inhibitors as Antiviral Agents to Control Influenza A Virus Replication

Olivia Perwitasari et al.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2015)

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Article Biochemical Research Methods

High-Throughput HIV-Cell Fusion Assay for Discovery of Virus Entry Inhibitors

Mariana Marin et al.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2015)

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Inhibition of HIV-1 entry by the tricyclic coumarin GUT-70 through the modification of membrane fluidity

Kouki Matsuda et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

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The evolution of three decades of antiretroviral therapy: challenges, triumphs and the promise of the future

Alice Tseng et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2015)

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Treatment With Anti-C5a Antibody Improves the Outcome of H7N9 Virus Infection in African Green Monkeys

Shihui Sun et al.

CLINICAL INFECTIOUS DISEASES (2015)

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Article Infectious Diseases

The 1918 influenza pandemic in New York City: age-specific timing, mortality, and transmission dynamics

Wan Yang et al.

INFLUENZA AND OTHER RESPIRATORY VIRUSES (2014)

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Dual Role of Novel Ingenol Derivatives from Euphorbia tirucalli in HIV Replication: Inhibition of De Novo Infection and Activation of Viral LTR

Celina M. Abreu et al.

PLOS ONE (2014)

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Structure and assembly of the influenza A virus ribonucleoprotein complex

Wenjie Zheng et al.

FEBS LETTERS (2013)

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A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A

Jerome Lane et al.

HUMAN MOLECULAR GENETICS (2013)

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Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

Paul J. McLaren et al.

PLOS PATHOGENS (2013)

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Article Pharmacology & Pharmacy

Role of Human Hypoxanthine Guanine Phosphoribosyltransferase in Activation of the Antiviral Agent T-705 (Favipiravir)

Lieve Naesens et al.

MOLECULAR PHARMACOLOGY (2013)

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Article Infectious Diseases

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

Fatimah S. Dawood et al.

LANCET INFECTIOUS DISEASES (2012)

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Natural SIV Hosts: Showing AIDS the Door

Ann Chahroudi et al.

SCIENCE (2012)

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TRIM5 is an innate immune sensor for the retrovirus capsid lattice

Thomas Pertel et al.

NATURE (2011)

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Ivermectin, 'Wonder drug' from Japan: the human use perspective

Andy Crump et al.

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2011)

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Coronaviruses An RNA proofreading machine regulates replication fidelity and diversity

Mark R. Denison et al.

RNA BIOLOGY (2011)

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Direct activation of protein kinases by unanchored polyubiquitin chains

Zong-Ping Xia et al.

NATURE (2009)

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Stem cells and aging in the hematopoietic system

Luigi A. Warren et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2009)

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Management of hepatitis C virus infection in HIV/HCV co-infected patients: Clinical review

Ashwani K. Singal et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2009)

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Article Immunology

Influenza pandemics of the 20th century

ED Kilbourne

EMERGING INFECTIOUS DISEASES (2006)

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