Journal
MOLECULES
Volume 27, Issue 12, Pages -Publisher
MDPI
DOI: 10.3390/molecu1es27123763
Keywords
N-carbamoyl-protected propargylic amines; alpha-amido sulfones; cyclopropylacetylene; BINOL; zinc complex
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A convenient procedure for synthesizing N-carbamoyl-protected propargylic amines substituted with a cyclopropyl group from alpha-amido sulfones and cyclopropylacetylene is described. The reaction is catalyzed by a chiral BINOL-type zinc complex, providing the corresponding products in good yields and enantioselectivities.
A convenient procedure of synthesis of N-carbamoyl-protected propargylic amines substituted with a cyclopropyl group from alpha-amido sulfones and cyclopropylacetylene is described. The reaction is catalyzed by a chiral BINOL-type zinc complex and provides the corresponding products in good yields and enantioselectivities.
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