Novel serum biomarkers for infection in paediatric emergency

Sepsis is one of the most frequent causes of morbidity and mortality in the paediatric age, and its early recognition is important to prevent its lethal outcomes. A great variety of novel serum biomarkers of infection have been investigated in the last decades, although most of the research has been performed in adult patients. We report current knowledge on this topic to assess the diagnostic efficacy of novel biomarkers of infection in paediatric patients.

Automated summary

Sepsis is a common and serious condition in pediatric patients, and early recognition is essential to prevent fatal outcomes. However, most research on novel serum biomarkers of infection has been conducted in adults. This article provides an overview of the current knowledge on the diagnostic efficacy of novel biomarkers of infection in pediatric patients.