The Prevalence and Related Effects of HIV Drug-Resistant Strains Against Antiretroviral Therapy in China

Anti-human immunodeficiency virus (HIV) treatment resistance surveillance has been going on for nearly 18 years in China. In this paper, we review the prevalence in China of resistance to reverse transcriptase and protease inhibitors in the HIV-infected population receiving antiretroviral therapy (ART) and the population that stopped ART in recent years. Drug resistance is an important factor affecting the death of patients with acquired immune deficiency syndrome (AIDS). With the extension of the duration of ART and the expansion of the population receiving ART, especially the widespread promotion of preventive drugs before and after exposure, it is important to obtain insight into the prevalence and types of drug-resistant strains and their impact on the overall AIDS prevention and treatment effect.

Automated summary

This paper reviews the prevalence of resistance to HIV reverse transcriptase and protease inhibitors in the HIV-infected population receiving antiretroviral therapy (ART) in China, as well as the population that stopped ART in recent years. Drug resistance is an important factor affecting the mortality of AIDS patients. It is crucial to understand the prevalence and types of drug-resistant strains and their impact on overall AIDS prevention and treatment, especially with the expansion of ART and the widespread use of preventive drugs.