Journal
NATURAL PRODUCT REPORTS
Volume 39, Issue 9, Pages 1803-1832Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2np00023g
Keywords
-
Funding
- National Natural Science Foundation of China [81991521]
- SKLDR/SIMM Project [SIMM2013ZZ-06]
Ask authors/readers for more resources
This article summarizes over 200 cases of misassigned marine natural products reported between July 2010 and August 2021, identifying major pitfalls in small molecule structural elucidation and highlighting the role of total synthesis, crystallography, and chemical- and biosynthetic logic in complementing spectroscopic data.
Covering: July 2010 to August 2021 This article summarizes more than 200 cases of misassigned marine natural products reported between July 2010 and August 2021, sorting out errors according to the structural elements. Based on a comparative analysis of the original and the revised structures, major pitfalls still plaguing the structural elucidation of small molecules were identified, emphasizing the role of total synthesis, crystallography, as well as chemical- and biosynthetic logic to complement spectroscopic data. Distinct trends in natural product misassignment are evident between compounds of marine and plant origin, with an overall much lower incidence of impossible structures within misassigned marine natural products.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available