Multi-layered alginate hydrogel structures and bacteria encapsulation

We show the design and fabrication of finely tuned alginate core-shell capsules with precisely controllable core and hierarchical shell thickness at micron scale for scaleup for mass production. The method developed was used to encapsulate bacteria while maintaining morphology and mechanical stability of the bead without rupturing and cell leakage.

Automated summary

This study demonstrates the design and fabrication of finely tuned alginate core-shell capsules with controllable core and shell thickness at the micron scale. These capsules were successfully used to encapsulate bacteria while maintaining their morphology and mechanical stability.