Journal
CHEMICAL COMMUNICATIONS
Volume 58, Issue 62, Pages 8682-8685Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cc01729f
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Funding
- National Natural Science Foundation of China [22106093, 21874086]
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This new active tumor-targeting organic photochemotherapy agent combines an organic photothermal material with a naproxen prodrug to precisely kill cancer cells and suppress inflammatory responses. In vitro and in vivo experiments have shown its low cytotoxicity and excellent tumor inhibitory effect.
An active tumor-targeting organic photochemotherapy agent via the combination of a an organic photothermal material and a naproxen prodrug was developed to precisely kill cancer cells and suppress the inflammatory response induced by cell necrosis; in vitro, and in vivo experiments illustrated its low cytotoxicity and excellent tumor inhibitory effect.
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