Two decades of omics in bacterial wilt resistance in Solanaceae, what we learned?

Wilt caused by the bacteria Ralstonia solanacearum, Enterobacter cloacae and Burkholderia glumae, independently or in complex, in Solanaceous vegetables is leading to enormous crop losses. The resistance mechanisms in tomato, chilli peppers, eggplant and potato are polygenically governed and the molecular level analyses have been successful to understand the key genes and pathways involved. QTL and candidate gene mapping, development of molecular markers explaining significant level of phenotypic variation, transcriptome analysis, expression analysis for the putative candidate genes and metabolome analyses which have been successful to reveal the genes and pathways in resistance are discussed in this paper. Genetic transformations using the key genes thus identified have been successful to generate the resistant lines. In addition to a systematic discussion on these topics, the major QTLs for bacterial wilt resistance in tomato and chilli peppers have been analyzed, contributing genes identified and annotated and the mechanisms conserved between these crops are discussed.

Automated summary

This paper discusses the resistance mechanisms to wilt caused by different bacteria in Solanaceous vegetables and introduces the molecular level analysis methods and research findings. The study finds that various molecular markers and metabolome analysis can reveal resistant genes and pathways, while genetic transformation can generate resistant lines. In addition, the paper analyzes the major QTLs for wilt resistance in tomato and chilli peppers and the conserved mechanisms.