Journal
JOURNAL OF THE ROYAL SOCIETY INTERFACE
Volume 19, Issue 192, Pages -Publisher
ROYAL SOC
DOI: 10.1098/rsif.2022.0233
Keywords
diffusion; mobile-immobile model; tau proteins
Categories
Funding
- German Science Foundation (DFG) [ME 1535/12-1]
- Polish National Agency for Academic Exchange(NAWA)
Ask authors/readers for more resources
We investigate the transport of particles that switch between mobile and immobile phases. Despite the assumption of Poissonian switching, we observe transient anomalous diffusion and non-Gaussian displacement distributions. These findings are expected to have relevance for a broad range of processes in complex systems.
We analyse mobile-immobile transport of particles that switch between the mobile and immobile phases with finite rates. Despite this seemingly simple assumption of Poissonian switching, we unveil a rich transport dynamics including significant transient anomalous diffusion and non-Gaussian displacement distributions. Our discussion is based on experimental parameters for tau proteins in neuronal cells, but the results obtained here are expected to be of relevance for a broad class of processes in complex systems. Specifically, we obtain that, when the mean binding time is significantly longer than the mean mobile time, transient anomalous diffusion is observed at short and intermediate time scales, with a strong dependence on the fraction of initially mobile and immobile particles. We unveil a Laplace distribution of particle displacements at relevant intermediate time scales. For any initial fraction of mobile particles, the respective mean squared displacement (MSD) displays a plateau. Moreover, we demonstrate a short-time cubic time dependence of the MSD for immobile tracers when initially all particles are immobile.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available