Selenium-Based Fluorescence Probes for the Detection of Bioactive Molecules

Chemistry of organoselenium reagents have now become an important tool of synthetic organic and medicinal chemistry. These reagents activate the olefinic double bonds and used to archive the number of organic transformations under mild reaction conditions. A number of organoselenium compounds have been identified as potent oxidants. Recently, various organoselenium species have been employed as chemical sensors for detecting toxic metals. Moreover, a number of selenium-based fluorescent probes have been developed for detecting harmful peroxides and ROS. In this review article, the synthesis of selenium-based fluorescent probes will be covered including their application in the detection of toxic metals and harmful peroxides including ROS.

Automated summary

The chemistry of organoselenium reagents has become crucial in synthetic organic and medicinal chemistry, enabling various organic transformations under mild reaction conditions by activating olefinic double bonds. Organoselenium compounds have been identified as potent oxidants, and recently, they have been utilized as chemical sensors for detecting toxic metals. Selenium-based fluorescent probes have also been developed for detecting harmful peroxides and ROS.