4.7 Article

Chronic Pulmonary Disease Caused by Tsukamurella toyonakaense

Journal

EMERGING INFECTIOUS DISEASES
Volume 28, Issue 7, Pages 1437-1441

Publisher

CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2807.212320

Keywords

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Funding

  1. Japan Agency for Medical Research and Development [JP20fk0108129, JP21fk0108129h0702, JP21lm0203007]
  2. GlaxoSmithKline [A-32]
  3. Japan Society for the Promotion of Science [JP21K16118, JP21K08194]
  4. Smoking Research Foundation
  5. Takeda Science Foundation
  6. Japan Intractable Diseases (Nanbyo) Research Foundation [2020B02]

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We identified a novel Tsukamurella species, Tsukamurella toyonakaense, which was misdiagnosed as nontuberculous mycobacterial pulmonary disease caused by unidentified mycobacteria. Genomic identification of this Tsukamurella species helped clarify its clinical characteristics and epidemiology.
Unidentified Mycobacterium species are sometimes detected in respiratory specimens. We identified a novel Tsukamurella species (Tsukamurella sp. TY48, RIMD 2001001, CIP 111916(T)), Tsukamurella toyonakaense, from a patient given a misdiagnosis of nontuberculous mycobacterial pulmonary disease caused by unidentified mycobacteria. Genomic identification of this Tsukamurella species helped clarify its clinical characteristics and epidemiology.

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