☆ 4.7 Article

An amelogenin-based peptide hydrogel promoted the odontogenic differentiation of human dental pulp cells

REGENERATIVE BIOMATERIALS (2022)

Related references

Note: Only part of the references are listed.

Article Multidisciplinary Sciences

Delivery of affordable and scalable encapsulated allogenic/autologous mesenchymal stem cells in coagulated platelet poor plasma for dental pulp regeneration

Ioannis Angelopoulos et al.

Summary: This study evaluated the potential of Platelet Poor Plasma (PPP) as a biomaterial for regenerative endodontics procedures (REPs). The study found that PPP scaffold was compatible with dental pulp stem cells (DPSC) and umbilical cord mesenchymal stem cells (UC-MSC), with differences in proliferation and angiogenic properties. Histological analysis showed the formation of dentin-like structure with MSC-PPP implants. This study provides evidence of a cost-effective scaffold for dental pulp regeneration.

SCIENTIFIC REPORTS (2022)

Add to Collection

Article Materials Science, Biomaterials

Biomimetic mineralized microenvironment stiffness regulated BMSCs osteogenic differentiation through cytoskeleton mediated mechanical signaling transduction

Lu Chen et al.

Summary: Construction of biomimetic microenvironment is essential to understand the relationship between matrix mechanical cues and cell fate. Higher mechanical strength in the biomimetic mineralized microenvironment promoted osteogenic differentiation of stem cells through enhanced cytoskeletal assembly and expression of YAP and RUNX2. This study provides a promising material platform for bone tissue engineering and exploring the mechanism of biomimetic bone matrix mechanics on osteogenesis.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Add to Collection

Review Dentistry, Oral Surgery & Medicine

Endodontic management of traumatized permanent teeth: a comprehensive review

G. Krastl et al.

Summary: Proper diagnosis of dental pulp is crucial in the treatment of traumatic dental injuries, requiring a thorough understanding of the physiological and pathological responses of the affected tissues. Additionally, consideration of the interaction between pulp and surrounding tissues is essential for treatment decisions.

INTERNATIONAL ENDODONTIC JOURNAL (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Inflammatory Response Mechanisms of the Dentine-Pulp Complex and the Periapical Tissues

Kerstin M. Galler et al.

Summary: The anatomy of the oral cavity is complex, with different tissues interacting closely. Teeth are vulnerable to damage, particularly from caries, but the dental pulp has multiple defense mechanisms to protect against pathogens.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection

Article Multidisciplinary Sciences

Leucine rich amelogenin peptide prevents ovariectomy-induced bone loss in mice

Naoto Haruyama et al.

Summary: Amelogenins, particularly LRAP, play important roles in bone turnover by regulating bone formation and osteoclastogenesis. Transgenic mice overexpressing LRAP showed enhanced bone formation, inhibited osteoclastogenesis, and resistance to bone loss, highlighting the potential therapeutic implications of LRAP in treating osteoporosis.

PLOS ONE (2021)

Add to Collection

Article Multidisciplinary Sciences

Chlorite oxidized oxyamylose differentially influences the microstructure of fibrin and self assembling peptide hydrogels as well as dental pulp stem cell behavior

Mostafa EzEldeen et al.

Summary: Tailored hydrogels mimicking the native extracellular environment have been studied for their potential in regenerative endodontics. This study evaluated the effects of a chemokine-binding and antimicrobial polymer, COAM, on the microstructural properties of fibrin and SAP hydrogels, as well as the behavior of hDPSCs. The inclusion of COAM did not alter the microstructure of fibrin hydrogels significantly, but affected the SAP hydrogels leading to fiber aggregation. Cell viability and attachment were higher in fibrin hydrogels compared to SAP hydrogels, suggesting the former as a promising carrier for COAM in endodontic regeneration.

SCIENTIFIC REPORTS (2021)

Add to Collection

Article Chemistry, Physical

Evaluation of Injectable Hyaluronic Acid-Based Hydrogels for Endodontic Tissue Regeneration

Esteban Astudillo-Ortiz et al.

Summary: The study investigated an injectable hyaluronic acid-based hydrogel system enriched with platelet lysate for endodontic regeneration. The hydrogels showed suitable working and setting times, a porous microstructure, and supportive properties for cell migration towards dentin surfaces, indicating great clinical potential for endodontic regenerative therapies.

MATERIALS (2021)

Add to Collection

Article Materials Science, Biomaterials

Evaluating the potential of an amelogenin-derived peptide in tertiary dentin formation

Xiu Peng et al.

Summary: Several novel biomaterials have been developed to induce tertiary dentin formation for dental pulp capping. QP5, an amelogenin-based peptide, was found to enhance migration and mineralization of human dental pulp cells, with little effect on cell viability. In vivo results in rat models showed that QP5 as a pulp capping agent promoted the formation of tertiary dentin more prominently compared to the negative control group.

REGENERATIVE BIOMATERIALS (2021)

Add to Collection

Article Polymer Science

3D Bioprinting of Polycaprolactone-Based Scaffolds for Pulp-Dentin Regeneration: Investigation of Physicochemical and Biological Behavior

Zohre Mousavi Nejad et al.

Summary: The PCL/BG and PCL/HyA scaffolds fabricated by 3D printing technology showed great potential for promoting dentin and pulp tissue regeneration, with the former exhibiting higher bioactivity and surface roughness, and the latter enhancing cell adhesion and hydrophilicity. Gene expression results demonstrated increased expression of odontogenic markers with both scaffolds, indicating their suitability for hDPSC adhesion and odontogenic differentiation.

POLYMERS (2021)

Add to Collection

Article Physiology

Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation

Aya Yamada et al.

Summary: Connexin 43 (Cx43) is an integral membrane protein that plays a crucial role in tooth development, regulating intercellular communication through gap junction activity by modulating TGF-beta 1-mediated ERK signaling and enamel formation.

FRONTIERS IN PHYSIOLOGY (2021)

Add to Collection

Review Dentistry, Oral Surgery & Medicine

Platelet-Rich Fibrin Used in Regenerative Endodontics and Dentistry: Current Uses, Limitations, and Future Recommendations for Application

Sohaib Arshad et al.

Summary: Regenerative endodontics has introduced various procedures such as pulp implantation, revascularization, and postnatal stem cell therapy. Revascularization, particularly through the use of PRF, has shown clinical success in promoting bone growth and vascularization. PRF, with its fibrin complex composition, has been effective in various surgical cases and is considered more economical and feasible for daily clinical practices compared to platelet-rich plasma.

INTERNATIONAL JOURNAL OF DENTISTRY (2021)

Add to Collection

Article Polymer Science

The Amelogenin-Derived Peptide TVH-19 Promotes Dentinal Tubule Occlusion and Mineralization

Xiu Peng et al.

Summary: The study demonstrates that TVH-19 is effective in promoting dentin sealing by binding to periodontal dentin, promoting mineral deposition, and reducing the space between dentin tubules.

POLYMERS (2021)

Add to Collection

Article Medicine, Research & Experimental

Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and removes LXR-induced lipogenesis

Ke Feng et al.

Summary: The study demonstrates that D-Nap-GFFY-T317 can effectively inhibit tumor growth by increasing IFN gamma expression in APCs without adverse effects on hepatic lipogenesis. It also enhances infiltration of anti-tumor immune cells into tumors and inhibits tumor angiogenesis.

THERANOSTICS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Controlling Enamel Remineralization by Amyloid-Like Amelogenin Mimics

Dong Wang et al.

ADVANCED MATERIALS (2020)

Add to Collection

Article Nanoscience & Nanotechnology

Delivery of MSCs with a Hybrid β-Sheet Peptide Hydrogel Consisting IGF-1C Domain and D-Form Peptide for Acute Kidney Injury Therapy

Hongfeng Wang et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Add to Collection

Article Nanoscience & Nanotechnology

RGD- and VEGF-Mimetic Peptide Epitope-Functionalized Self-Assembling Peptide Hydrogels Promote Dentin-Pulp Complex Regeneration

Kun Xia et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Stimuli-Responsive, Pentapeptide, Nanofiber Hydrogel for Tissue Engineering

James D. Tang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Supramolecular Nanofibers with Superior Bioactivity to Insulin-Like Growth Factor-I

Yuna Shang et al.

NANO LETTERS (2019)

Add to Collection

Article Engineering, Biomedical

Self-assembled GFFYK peptide hydrogel enhances the therapeutic efficacy of mesenchymal stem cells in a mouse hindlimb ischemia model

Anan Huang et al.

ACTA BIOMATERIALIA (2019)

Add to Collection

Article Biochemistry & Molecular Biology

Control of endothelial cell tube formation by Notch ligand intracellular domain interactions with activator protein 1 (AP-1)

Zary Forghany et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Add to Collection

Article Anatomy & Morphology

Immunolocalization of connective tissue growth factor, transforming growth factor-betal and phosphorylated-SMAD2/3 during the postnatal tooth development and formation of junctional epithelium

Shubo Li et al.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER (2018)

Add to Collection

Article Engineering, Biomedical

Hyaluronic acid hydrogels incorporating platelet lysate enhance human pulp cell proliferation and differentiation

Leopoldina D. F. Almeida et al.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2018)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

The C-terminus of the amelogenin peptide influences the proliferation of human bone marrow mesenchymal stem cells

Ryo Kunimatsu et al.

JOURNAL OF PERIODONTOLOGY (2018)

Add to Collection

Article Medicine, Research & Experimental

Designer D-form self-assembling peptide scaffolds promote the proliferation and migration of rat bone marrow-derived mesenchymal stem cells

Shuo Chen et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017)

Add to Collection

Article Chemistry, Analytical

Peptide-Induced AIEgen Self-Assembly: A New Strategy to Realize Highly Sensitive Fluorescent Light-Up Probes

Aitian Han et al.

ANALYTICAL CHEMISTRY (2016)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

Recombinant Amelogenin Protein Induces Apical Closure and Pulp Regeneration in Open-apex, Nonvital Permanent Canine Teeth

Maha M. F. Mounit et al.

JOURNAL OF ENDODONTICS (2016)

Add to Collection

Article Cell & Tissue Engineering

Full-length amelogenin influences the differentiation of human dental pulp stem cells

Iris Frasheri et al.

STEM CELL RESEARCH & THERAPY (2016)

Add to Collection

Article Pharmacology & Pharmacy

Sodium dodecyl sulfate/β-cyclodextrin vesicles embedded in chitosan gel for insulin delivery with pH-selective release

Zhuo Li et al.

ACTA PHARMACEUTICA SINICA B (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Drug-Triggered and Cross-Linked Self-Assembling Nanofibrous Hydrogels

Vivek A. Kumar et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Add to Collection

Article Engineering, Biomedical

The Powerful Functions of Peptide-Based Bioactive Matrices for Regenerative Medicine

Charles M. Rubert Perez et al.

ANNALS OF BIOMEDICAL ENGINEERING (2015)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

Effects of the enamel matrix derivative on the proliferation and odontogenic differentiation of human dental pulp cells

Yuanyuan Wang et al.

JOURNAL OF DENTISTRY (2014)

Add to Collection

Article Anatomy & Morphology

Amelogenin Exons 8 and 9 Encoded Peptide Enhances Leucine Rich Amelogenin Peptide Mediated Dental Pulp Repair

Yulei Huang et al.

CELLS TISSUES ORGANS (2012)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

Odontoblast-like cell differentiation and dentin formation induced with TGF-β1

Yucheng Li et al.

ARCHIVES OF ORAL BIOLOGY (2011)

Add to Collection

Article Cell Biology

Transcriptional regulation of dentin matrix protein 1 (DMP1) by AP-1 (c-fos/c-jun) factors

K Narayanan et al.

CONNECTIVE TISSUE RESEARCH (2002)

Add to Collection

© Peeref 2019-2024. All rights reserved.