Journal
CHEMICAL COMMUNICATIONS
Volume 58, Issue 68, Pages 9488-9491Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cc03068c
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Funding
- Excellent Young Scientists Fund [22022407]
- National Natural Science Foundation of China [21874008, 22004006]
- Open Research Fund Program of Institute of cosmetic regulatory science, Beijing Technology and Business University [CRS-2021-02]
- Special Foundation for State Major Research Program of China [2019YFC1606603]
- SZU Top Ranking Project [86000000 2100165]
- 2021 Stability Support Plan of Shenzhen University [8940206/0200]
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A nanomachine consisting of cancer cell membrane vesicle-encapsulated gold nanoparticles with programmable DNA was developed, enabling homing-targeting ability and fast dynamic response for microRNA amplification analysis in living cancer cells. The DNA nanomachine holds great potential for early-stage cancer diagnosis.
A nanomachine consisting of cancer cell membrane vesicle-encapsulated gold nanoparticles with programmable DNA was established. Both homing-targeting ability and a fast dynamic response were achieved for amplification analysis of microRNAs in living cancer cells. The DNA nanomachine holds great potential to realize cancer diagnosis in early stages.
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