Morphological Study of Dental Structure in Dentinogenesis Imperfecta Type I with Scanning Electron Microscopy

Background: Dentinogenesis imperfecta type I (DGI-I) is a hereditary alteration of dentin associated with osteogenesis imperfecta (OI). Aim: To describe and study the morphological characteristics of DGI-I with scanning electron microscopy (SEM). Material and methods: Twenty-five teeth from 17 individuals diagnosed with OI and 30 control samples were studied with SEM at the level of the enamel, dentin-enamel junction (DEJ) and four levels of the dentin, studying its relationship with clinical-radiographic alterations. The variables were analysed using Fisher's exact test, with a confidence level of 95% and asymptotic significance. Results: OI teeth showed alterations in the prismatic structure in 56%, interruption of the union in the enamel and dentin in 64% and alterations in the tubular structure in all of the cases. There is a relationship between the severity of OI and the morphological alteration of the dentin in the superficial (p = 0.019) and pulpar dentin (p 0.004) regions. Conclusions: Morphological alterations of the tooth structure are found in OI samples in the enamel, DEJ and dentin in all teeth regardless of the presence of clinical-radiographic alterations. Dentin structural anomalies and clinical dental alterations were observed more frequently in samples from subjects with a more severe phenotype of OI.

Automated summary

This study explores the morphological characteristics of dentinogenesis imperfecta type I (DGI-I) using scanning electron microscopy (SEM) and reveals a relationship between dentin structural anomalies and the severity of osteogenesis imperfecta (OI). The findings suggest that dentin structural alterations and clinical dental changes are more frequently observed in individuals with a severe phenotype of OI.