4.7 Article

Gold nanoparticles: current and upcoming biomedical applications in sensing, drug, and gene delivery

Journal

CHEMICAL COMMUNICATIONS
Volume 58, Issue 78, Pages 10886-10895

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cc04826d

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Funding

  1. UST Overseas Training Program [2021205]
  2. University of Science and Technology
  3. PAPIIT UNAM [IN205320]

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This review briefly highlights the recent progress of gold nanoparticles (AuNPs) in biomedicine as bio-sensors and targeted nano vehicles, emphasizing their unique properties and challenges in detection applications and controlled drug or gene delivery.
Gold nanoparticles (AuNPs) present unique physicochemical characteristics, low cytotoxicity, chemical stability, size/morphology tunability, surface functionalization capability, and optical properties which can be exploited for detection applications (colorimetry, surface-enhanced Raman scattering, and photoluminescence). The current challenge for AuNPs is incorporating these properties in developing more sensible and selective sensing methods and multifunctional platforms capable of controlled and precise drug or gene delivery. This review briefly highlights the recent progress of AuNPs in biomedicine as bio-sensors and targeted nano vehicles.

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