4.5 Article

SF3B4 Depletion Retards the Growth of A549 Non-Small Cell Lung Cancer Cells via UBE4B-Mediated Regulation of p53/p21 and p27 Expression

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

An Adult Mouse Model of Dilated Cardiomyopathy Caused by Inducible Cardiac-Specific Bis Deletion

Hye Hyeon Yun et al.

Summary: The study developed tamoxifen-inducible cardiomyocyte-specific BIS-KO mice and found that disruption of the Bis gene led to impaired heart function and heart failure. These mice may serve as a useful model for developing therapeutic interventions for dilated cardiomyopathy.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Biochemistry & Molecular Biology

Alterations of RNA splicing patterns in esophagus squamous cell carcinoma

Jiyu Ding et al.

Summary: This study identified significant differentially expressed alternative splicing (AS) events between ESCC and normal tissues, with a focus on processes related to pro-metastasis cell junction and migration. The upregulated splicing factor SF3B4 was highlighted as a potential prognostic factor of ESCC.

CELL AND BIOSCIENCE (2021)

Article Multidisciplinary Sciences

UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation

Manivannan Subramanian et al.

Summary: The study identifies the miR-9 family as suppressors of Tau-mediated neurodegeneration in Alzheimer's disease. Through experiments in Drosophila and mammalian cells, it is revealed that UBE4B and STUB1 promote autophagic degradation of Tau through ubiquitination, suggesting a potential therapeutic target for AD.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Downregulation of BIS sensitizes A549 cells for digoxin-mediated inhibition of invasion and migration by the STAT3-dependent pathway

Hye Hyeon Yun et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

Review Oncology

The Role of E3, E4 Ubiquitin Ligase (UBE4B) in Human Pathologies

Nikolaos Antoniou et al.

CANCERS (2020)

Article Oncology

SF3B4 Plays an Oncogenic Role in Esophageal Squamous Cell Carcinoma

Shinya Kidogami et al.

ANTICANCER RESEARCH (2020)

Article Biotechnology & Applied Microbiology

Antibody-based biosensor to detect oncogenic splicing factor Sam68 for the diagnosis of lung cancer

B. Sumithra et al.

BIOTECHNOLOGY LETTERS (2020)

Article Medical Laboratory Technology

Broad-spectrum next-generation sequencing-based diagnosis of a case of Nager syndrome

Jue Zhao et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2020)

Article Medicine, General & Internal

Second-trimester prenatal diagnosis of Nager syndrome with a deletion including SF3B4 detected by chromosomal microarray

Malgorzata Drozniewska et al.

CLINICAL CASE REPORTS (2020)

Article Multidisciplinary Sciences

Component of splicing factor SF3b plays a key role in translational control of polyribosomes on the endoplasmic reticulum

Tomonori Ueno et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemistry & Molecular Biology

Antitumor activity of SR splicing-factor 5 knockdown by downregulating pyruvate kinase M2 in non-small cell lung cancer cells

Jiliang Yan et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

Article Biochemistry & Molecular Biology

A synonymous splicing mutation in the SF3B4 gene segregates in a family with highly variable Nager syndrome

Matteo Cassina et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2017)

Article Biochemistry & Molecular Biology

A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis

Thomas Treiber et al.

MOLECULAR CELL (2017)

Article Biochemistry & Molecular Biology

Expression and Prognostic Role of Ubiquitination Factor E4B in Primary Hepatocellular Carcinoma

Xiao-Fei Zhang et al.

MOLECULAR CARCINOGENESIS (2016)

Review Biochemistry & Molecular Biology

Splicing-factor alterations in cancers

Olga Anczukow et al.

Article Multidisciplinary Sciences

Regulation of p53 Level by UBE4B in Breast Cancer

Ying Zhang et al.

PLOS ONE (2014)

Article Genetics & Heredity

Haploinsufficiency of SF3B4, a Component of the Pre-mRNA Spliceosomal Complex, Causes Nager Syndrome

Francois P. Bernier et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2012)

Article Biochemistry & Molecular Biology

A Census of Human Soluble Protein Complexes

Pierre C. Havugimana et al.

Article Biochemistry & Molecular Biology

UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53

Hong Wu et al.

NATURE MEDICINE (2011)

Review Hematology

Ubiquitin-mediated proteasomal degradation in normal and malignant hematopoiesis

Melina L. Heuze et al.

BLOOD CELLS MOLECULES AND DISEASES (2008)

Article Biochemistry & Molecular Biology

Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation

Hiroki Watanabe et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Molecular clearance of ataxin-3 is regulated by a mammalian E4

M Matsumoto et al.

EMBO JOURNAL (2004)

Article Biochemistry & Molecular Biology

Human mdm2 mediates multiple mono-ubiquitination of p53 by a mechanism requiring enzyme isomerization

ZH Lai et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)