4.1 Article

Psychobiotics improve propionic acid-induced neuroinflammation in juvenile rats, rodent model of autism

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

The Efficacy of Fecal Transplantation and Bifidobacterium Supplementation in Ameliorating Propionic Acid-Induced Behavioral and Biochemical Autistic Features in Juvenile Male Rats

Sameera Abuaish et al.

Summary: Gut microbiota plays a significant role in neurological disorders, including autism, and modulation of the gut microbiota through fecal microbiota transplantation or probiotic administration could alleviate autistic symptoms and have positive effects on the brain.

JOURNAL OF MOLECULAR NEUROSCIENCE (2022)

Article Neurosciences

Bee pollen increases hippocampal brain-derived neurotrophic factor and suppresses neuroinflammation in adult rats with chronic immobilization stress

Ozlem Saral et al.

Summary: The study found that bee pollen reduced anxiety-like behavior in rats but did not affect depression-like behavior. Additionally, bee pollen suppressed neuroinflammation and reduced oxidative stress and lipid peroxidation in hippocampal tissues. Moreover, bee pollen significantly increased the level of BDNF in the hippocampus.

NEUROSCIENCE LETTERS (2022)

Article Biotechnology & Applied Microbiology

Production of biologically active human interleukin-10 by Bifidobacterium bifidum BGN4

Nayoun Hong et al.

Summary: Recombinant B. bifidum BGN4 [pBESIL10] efficiently produces and secretes significant amounts of biologically active human IL-10, with the highest production level reported to date. Further research should explore the potential of B. bifidum BGN4 [pBESIL10] producing IL-10 as a treatment for various inflammation-related diseases, including inflammatory bowel disease, rheumatoid arthritis, allergic asthma, and cancer immunotherapy.

MICROBIAL CELL FACTORIES (2021)

Article Pharmacology & Pharmacy

Proneurogenic and neuroprotective effect of a multi strain probiotic mixture in a mouse model of acute inflammation: Involvement of the gut-brain axis

Carla Petrella et al.

Summary: This study demonstrates that prolonged administration of a multi-strain probiotic formulation can prevent neuroinflammation, enhance neurogenesis, and strengthen the intestinal barrier.

PHARMACOLOGICAL RESEARCH (2021)

Review Clinical Neurology

The effects of psychobiotics on the microbiota-gut-brain axis in early-life stress and neuropsychiatric disorders

Annie Tremblay et al.

Summary: Psychobiotics are considered as a potential avenue to modulate the communication between the gut and central nervous system, with a focus on early intervention for neuropsychiatric disorders. While animal studies have shown promise in countering stress effects during early developmental periods, evidence for psychobiotics efficacy in improving mental outcomes in NPDs other than depression in humans is limited.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2021)

Article Food Science & Technology

The anti-inflammatory and antiapoptotic effects of probiotic on induced neurotoxicity in juvenile hamsters

Abir Ben Bacha et al.

Summary: This study demonstrates that probiotics can reduce apoptosis and neuroinflammation induced by propionic acid (PPA) by modulating gut function. In a hamster model, probiotics significantly decreased levels of apoptotic markers and inflammation markers, providing protection against brain damage.

FOOD SCIENCE & NUTRITION (2021)

Article Food Science & Technology

Testing the combined effects of probiotics and prebiotics against neurotoxic effects of propionic acid orally administered to rat pups

Anwar Al Suhaibani et al.

Summary: The study examined the combined effects of mixed probiotic and bee pollen on brain intoxication induced by propionic acid in rat pups. The results showed that the treatment was effective in improving oxidative stress, energy metabolism, and neuroinflammation.

FOOD SCIENCE & NUTRITION (2021)

Article Neurosciences

Fecal Transplant and Bifidobacterium Treatments Modulate Gut Clostridium Bacteria and Rescue Social Impairment and Hippocampal BDNF Expression in a Rodent Model of Autism

Sameera Abuaish et al.

Summary: Autism is linked to gastrointestinal dysfunction and gut microbiota dysbiosis, where modulation of microbiota can improve symptoms. Findings suggest that interventions like fecal microbiota transplantation can restore bacterial balance and normalize BDNF expression levels in a preclinical model of autism.

BRAIN SCIENCES (2021)

Article Clinical Neurology

Polymorphism of interleukin-1 β and interleukin-1 receptor antagonist genes in children with autism spectrum disorders

Khaled Saad et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2020)

Review Neurosciences

The Immune System, Cytokines, and Biomarkers in Autism Spectrum Disorder

Anne Masi et al.

NEUROSCIENCE BULLETIN (2017)

Review Cell Biology

M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b

Chiara Parisi et al.

MEDIATORS OF INFLAMMATION (2016)

Article Multidisciplinary Sciences

Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice

Jun Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Neurosciences

Psychobiotics and the Manipulation of Bacteria-Gut-Brain Signals

Amar Sarkar et al.

TRENDS IN NEUROSCIENCES (2016)

Review Neurosciences

Interactions of innate and adaptive immunity in brain development and function

Anthony J. Filiano et al.

BRAIN RESEARCH (2015)

Review Biochemistry & Molecular Biology

Polyphenols from Bee Pollen: Structure, Absorption, Metabolism and Biological Activity

Anna Rzepecka-Stojko et al.

MOLECULES (2015)

Article Multidisciplinary Sciences

Structural and functional features of central nervous system lymphatic vessels

Antoine Louveau et al.

NATURE (2015)

Review Pharmacology & Pharmacy

Kaempferol and inflammation: From chemistry to medicine

Kasi Pandima Devi et al.

PHARMACOLOGICAL RESEARCH (2015)

Review Neurosciences

Systematic review of the neurobiological relevance of chemokines to psychiatric disorders

Michael J. Stuart et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2015)

Article Food Science & Technology

Biological activities of commercial bee pollens: Antimicrobial, antimutagenic, antioxidant and anti-inflammatory

Ananias Pascoal et al.

FOOD AND CHEMICAL TOXICOLOGY (2014)

Review Neurosciences

Psychobiotics: A Novel Class of Psychotropic

Timothy G. Dinan et al.

BIOLOGICAL PSYCHIATRY (2013)

Review Pediatrics

Autism spectrum disorders: a pediatric overview and update

Alexis Tchaconas et al.

CURRENT OPINION IN PEDIATRICS (2013)

Editorial Material Gastroenterology & Hepatology

Consumption of Fermented Milk Product With Probiotic Modulates Brain Activity

Kirsten Tillisch et al.

GASTROENTEROLOGY (2013)

Article Biochemistry & Molecular Biology

Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion

Hariom Yadav et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Cell Biology

Systemic Immune Activation Leads to Neuroinflammation and Sickness Behavior in Mice

Steven Biesmans et al.

MEDIATORS OF INFLAMMATION (2013)

Article Clinical Neurology

Does a Pro-Inflammatory Process Precede Alzheimers Disease and Mild Cognitive Impairment?

M. T. Ferretti et al.

Current Alzheimer Research (2012)

Article Food Science & Technology

Antimicrobial activity, phenolic profile and role in the inflammation of propolis

Joao Carlos Silva et al.

FOOD AND CHEMICAL TOXICOLOGY (2012)

Article Immunology

Etiology of autistic features: the persisting neurotoxic effects of propionic acid

Afaf K. El-Ansary et al.

JOURNAL OF NEUROINFLAMMATION (2012)

Review Neurosciences

Understanding the neuroinflammatory response following concussion to develop treatment strategies

Zachary R. Patterson et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2012)

Article Cell Biology

CCL5 induces a pro-inflammatory profile in microglia in vitro

Jelena Skuljec et al.

CELLULAR IMMUNOLOGY (2011)

Article Psychiatry

Aberrant NF-KappaB Expression in Autism Spectrum Condition: A Mechanism for Neuroinflammation

Adam M. H. Young et al.

Frontiers in Psychiatry (2011)

Article Multidisciplinary Sciences

Probiotics promote gut health through stimulation of epithelial innate immunity

Cristiano Pagnini et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Microbiology

Probiotic and Gut Lactobacilli and Bifidobacteria: Molecular Approaches to Study Diversity and Activity

Michiel Kleerebezem et al.

ANNUAL REVIEW OF MICROBIOLOGY (2009)

Article Environmental Sciences

Evaluation of protective effect of bee pollen against propoxur toxicity in rat

Goekhan Eraslan et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2009)

Review Immunology

Interleukin-10: new perspectives on an old cytokine

David M. Mosser et al.

IMMUNOLOGICAL REVIEWS (2008)

Review Pharmacology & Pharmacy

Inflammation as a causative factor in the aetiology of Parkinson's disease

P. S. Whitton

BRITISH JOURNAL OF PHARMACOLOGY (2007)

Article Clinical Neurology

Neuroglial activation and neuroinflammation in the brain of patients with autism

DL Vargas et al.

ANNALS OF NEUROLOGY (2005)

Article Neurosciences

High nitric oxide production in autistic disorder:: A possible role for interferon-γ

TL Sweeten et al.

BIOLOGICAL PSYCHIATRY (2004)

Article Immunology

IL-10 promotes survival of microglia without activating Akt

K Strle et al.

JOURNAL OF NEUROIMMUNOLOGY (2002)