Journal
ADVANCED SCIENCE
Volume 3, Issue 9, Pages -Publisher
WILEY
DOI: 10.1002/advs.201600063
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Funding
- DOD-CDMRP-PCRP Concept Award [W81XWH-12-PRCRP-CDA]
- National Institutes of Health (NIH) Transformative R01 Grant [R01DK085714]
- Martin Escudero fellowship
- Lustgarten Foundation
- National Science Foundation
- Rio Hortega fellowship
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The clinical potential of circulating tumor cells (CTCs) in managing cancer metastasis is significant. However, low CTC isolation purities from patient blood have hindered sensitive molecular assays of these rare cells. Described herein is the ultra-pure isolation of CTCs from patient blood samples and how this platform has enabled highly specific molecular (mRNA and miRNA) profiling of patient CTCs.
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