Related references
Note: Only part of the references are listed.Results of the phase I CCTG IND.231 trial of CX-5461 in patients with advanced solid tumors enriched for DNA-repair deficiencies
John Hilton et al.
NATURE COMMUNICATIONS (2022)
Interfaces between cellular responses to DNA damage and cancer immunotherapy
Domenic Pilger et al.
GENES & DEVELOPMENT (2021)
G-quadruplex binders as cytostatic modulators o innate immune genes in cancer cells
Giulia Miglietta et al.
NUCLEIC ACIDS RESEARCH (2021)
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells
Jussara Amato et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies
Josue Carvalho et al.
TRENDS IN MOLECULAR MEDICINE (2020)
Molecular mechanisms and cellular functions of cGAS-STING signalling
Karl-Peter Hopfner et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Improved Anti-Prion Nucleic Acid Aptamers by Incorporation of Chemical Modifications
Jussara Amato et al.
NUCLEIC ACID THERAPEUTICS (2020)
G-quadruplex-R-loop interactions and the mechanism of anticancer G-quadruplex binders
Giulia Miglietta et al.
NUCLEIC ACIDS RESEARCH (2020)
Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
Xiang Gui et al.
NATURE (2019)
Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells
Jennifer Beauvarlet et al.
NUCLEIC ACIDS RESEARCH (2019)
DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells
Alessio De Magis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand
Michela Zuffo et al.
NUCLEIC ACIDS RESEARCH (2018)
cGAS surveillance of micronuclei links genome instability to innate immunity
Karen J. Mackenzie et al.
NATURE (2017)
Mitotic progression following DNA damage enables pattern recognition within micronuclei
Shane M. Harding et al.
NATURE (2017)
Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives
Jussara Amato et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Quadruplex Nucleic Acids as Novel Therapeutic Targets
Stephen Neidle
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Innate Immune Recognition of Cancer
Seng-Ryong Woo et al.
ANNUAL REVIEW OF IMMUNOLOGY VOL 33 (2015)
STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade
Juan Fu et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells
Giulia Biffi et al.
NATURE CHEMISTRY (2014)
Turning Tumors into Vaccines: Co-opting the Innate Immune System
Jasper G. van den Boorn et al.
IMMUNITY (2013)
Molecular Interaction Studies Using Microscale Thermophoresis
Moran Jerabek-Willemsen et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2011)
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Shankar Balasubramanian et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Bis-guanylhydrazone diimidazo[1,2-a:1,2-c]pyrimidine as a novel and specific G-quadruplex binding motif
Silvia Sparapani et al.
CHEMICAL COMMUNICATIONS (2010)
A G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad Dynamics
Shang-Te Danny Hsu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution:: insights into structure polymorphism of the human telomeric sequence
Jixun Dai et al.
NUCLEIC ACIDS RESEARCH (2007)
Fluorescence-based melting assays for studying quadruplex ligands
Anne De Cian et al.
METHODS (2007)
Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands
David Monchaud et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Solution structure of the biologically relevant g-quadruplex element in the human c-MYC promoter. implications for g-quadruplex stabilization
A Ambrus et al.
BIOCHEMISTRY (2005)