Research Progress of Reactions Participated by α-Hydroxy Ketones

alpha-Hydroxyl ketones are an important class of compounds. They are not only the key structural fragments of many biologically active natural products, but also the important synthetic building blocks, hence a-hydroxyl ketones are employed in the synthesis of various biologically active molecules and drugs. The nucleophilic addition reactions and the cycloaddition reactions involving a-hydroxyl ketones are sorted out and summarized.

Automated summary

This article summarizes the nucleophilic addition reactions and cycloaddition reactions involving alpha-hydroxyl ketones. Alpha-hydroxyl ketones are not only key structural fragments of many natural products, but also important building blocks for the synthesis of biologically active molecules and drugs.