4.7 Article

BODIPY-based metal-organic frameworks as efficient electrochemiluminescence emitters for telomerase detection

Journal

CHEMICAL COMMUNICATIONS
Volume 58, Issue 82, Pages 11515-11518

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cc04722e

Keywords

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Funding

  1. Natural Science Foundation of Jiangsu Province [BZ2021010]
  2. National Natural Science Foundation of China [22274071, 22234005, 22071103, 22001119]

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In this research, a boron dipyrromethene (BODIPY)-based metal-organic framework (MOF) nanoemitter was designed for the first time. The ordered arrangement of BODIPY molecules in the framework helps to enhance the electrochemiluminescence (ECL) intensity by suppressing non-radiative dissipation. Consequently, an ECL biosensor was developed for telomerase detection and showed excellent performance in real samples.
A boron dipyrromethene (BODIPY)-based metal-organic framework (MOF) nanoemitter was for the first time designed with enhanced electrochemiluminescence (ECL) intensity due to the suppression of non-radiative dissipation originating from the ordered arrangement of BODIPY molecules in the framework. Thus, an ECL biosensor was developed for telomerase detection with excellent performance in real samples.

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