Journal
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY
Volume 10, Issue 2, Pages 219-229Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/1756283X16681709
Keywords
age; early gastric cancer; prognosis; sex
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Background: Few studies have compared early gastric cancer (EGC) outcomes according to sex and age. Methods: We retrospectively reviewed 2085 patients who underwent curative gastrectomy for EGC between 1989 and 2000. Prognosis and risk factors for nodal involvement were evaluated according to sex and age. Results: Male sex and age were independent prognostic factors for overall survival (OS) but not relapse-free survival (RFS). In young (<= 55 years) patients, there were no significant differences in RFS and OS between men and women. However, older (<= 55 years) men had a poorer OS and older women had a poorer RFS. Young female patients had a higher proportion of gastric cancer-related death than young male patients. Female sex was an independent risk factor for nodal involvement in younger patients. Conclusions: Young women with EGC should be more intensively treated and monitored than other patient groups and should not be treated by endoscopic resection.
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