Visible-light-induced 1,2-diphenyldisulfane-catalyzed regioselective hydroboration of electron-deficient alkenes

A green and practical photoinduced method for regioselective hydroboration of electron-deficient alkenes with NHC-borane has been developed in which 1,2-diphenyldisulfane was employed as a photocatalyst and hydrogen atom transfer (HAT) reagent precursor. This mild protocol shows excellent selectivity, good functional group tolerance, and broad substrate scope. A series of borylated carbonyl, nitrile, sulfone, phosphonate, trifluoromethyl, and gem-diboron compounds have been synthesized in moderate to excellent yields.

Automated summary

A green and practical photoinduced method for regioselective hydroboration of electron-deficient alkenes has been developed using 1,2-diphenyldisulfane as a photocatalyst and HAT reagent precursor. This mild protocol allows for the synthesis of various borylated compounds under excellent selectivity and functional group tolerance.