3.8 Article

Spironolactone alleviates schizophrenia-related reversal learning in Tcf4 transgenic mice subjected to social defeat

Related references

Note: Only part of the references are listed.
Article Neuroimaging

Abberant inverted U-shaped brain pattern and trait-related retinal impairment in schizophrenia patients with combined auditory and visual hallucinations: a pilot study

Chuanjun Zhuo et al.

Summary: Untreated first episode schizophrenic patients with combined auditory and visual hallucinations exhibit alterations in brain structure and function, as well as retinal abnormalities. The majority of these patients show reduced gray matter volume, increased global functional connectivity density, and thinning of the retina compared to healthy controls.

BRAIN IMAGING AND BEHAVIOR (2021)

Article Behavioral Sciences

PsyCoP - A Platform for Systematic Semi-Automated Behavioral and Cognitive Profiling Reveals Gene and Environment Dependent Impairments of Tcf4 Transgenic Mice Subjected to Social Defeat

Paul Volkmann et al.

Summary: Numerous risk genes associated with psychiatric disorders have been identified recently, with their interactions with environmental stress factors being a key focus. Utilizing a standardized and partially automized platform, researchers assessed behavioral and cognitive disturbances in Tcf4 transgenic mice exposed to psychosocial stress in adolescence, revealing potential phenotypic outcomes.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2021)

Article Pharmacology & Pharmacy

Head-to-Head Comparison of Sedation and Somnolence Among 37 Antipsychotics in Schizophrenia, Bipolar Disorder, Major Depression, Autism Spectrum Disorders, Delirium, and Repurposed in COVID-19, Infectious Diseases, and Oncology From the FAERS, 2004-2020

Andy R. Eugene et al.

Summary: This study assessed the disproportionality of sedation and somnolence among thirty-seven typical and atypical antipsychotics based on ADR data. Results showed that typical antipsychotic compounds had a stronger association with sedation and somnolence compared to atypical antipsychotics, with Zuclopenthixol being the most strongly associated compound. This comprehensive analysis provides informative insights for the repurposing and use of antipsychotic compounds in various clinical indications.

FRONTIERS IN PHARMACOLOGY (2021)

Article Medicine, Research & Experimental

Why is prepulse inhibition disrupted in schizophrenia?

Kohji Sato

MEDICAL HYPOTHESES (2020)

Review Biochemistry & Molecular Biology

Clinical Trials and Therapeutic Rationale for Drug Repurposing in Schizophrenia

Santiago G. Lago et al.

ACS CHEMICAL NEUROSCIENCE (2019)

Article Endocrinology & Metabolism

Mineralocorticoid receptor function and cognition in health and disease

Katja Wingenfeld et al.

PSYCHONEUROENDOCRINOLOGY (2019)

Article Neurosciences

Genes Involved in Neurodevelopment, Neuroplasticity and Major Depression: No Association for CACNA1C, CHRNA7 and MAPK1

Marco Calabro et al.

CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE (2019)

Article Multidisciplinary Sciences

Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia

Abolfazl Doostparast Torshizi et al.

SCIENCE ADVANCES (2019)

Article Multidisciplinary Sciences

Cage aggression in group-housed laboratory male mice: an international data crowdsourcing project

Katie Lidster et al.

SCIENTIFIC REPORTS (2019)

Article Psychology, Developmental

Prenatal inflammation and risk for schizophrenia: A role for immune proteins in neurodevelopment

Dana M. Allswede et al.

DEVELOPMENT AND PSYCHOPATHOLOGY (2018)

Editorial Material Psychiatry

Future of Days Past: Neurodevelopment and Schizophrenia

Daniel R. Weinberger

SCHIZOPHRENIA BULLETIN (2017)

Article Medicine, Research & Experimental

Spironolactone is an antagonist of NRG1-ERBB4 signaling and schizophrenia-relevant endophenotypes in mice

Michael C. Wehr et al.

EMBO MOLECULAR MEDICINE (2017)

Editorial Material Medicine, Research & Experimental

From neuroleptics to neuroscience and from Pavlov to psychotherapy: more than just the emperor's new treatments for mental illnesses?

Juergen Margraf et al.

EMBO MOLECULAR MEDICINE (2016)

Review Pharmacology & Pharmacy

Drug repurposing and emerging adjunctive treatments for schizophrenia

Jan Malte Bumb et al.

EXPERT OPINION ON PHARMACOTHERAPY (2015)

Article Neurosciences

Dopaminergic modulation of locomotor network activity in the neonatal mouse spinal cord

Simon A. Sharples et al.

JOURNAL OF NEUROPHYSIOLOGY (2015)

Review Biochemistry & Molecular Biology

Kraepelin revisited: schizophrenia from degeneration to failed regeneration

P. Falkai et al.

MOLECULAR PSYCHIATRY (2015)

Review Genetics & Heredity

Arguments for the Sake of Endophenotypes: Examining Common Misconceptions About the Use of Endophenotypes in Psychiatric Genetics

David C. Glahn et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2014)

Article Medicine, General & Internal

Autism

Meng-Chuan Lai et al.

LANCET (2014)

Article Developmental Biology

Development of Hyperactivity and Anxiety Responses in Dopamine Transporter-Deficient Mice

Alex C. Carpenter et al.

DEVELOPMENTAL NEUROSCIENCE (2012)

Article Peripheral Vascular Disease

Improvement of cognitive impairment in female type 2 diabetes mellitus mice by spironolactone

Akiko Sakata et al.

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (2012)

Article Multidisciplinary Sciences

Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating

Boris B. Quednow et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Chemistry, Multidisciplinary

Neurobehavioral and genotoxic parameters of antipsychotic agent aripiprazole in mice

Jaqueline Nascimento Picada et al.

ACTA PHARMACOLOGICA SINICA (2011)

Article Biochemistry & Molecular Biology

Brain-derived neurotrophic factor levels in schizophrenia: a systematic review with meta-analysis

M. J. Green et al.

MOLECULAR PSYCHIATRY (2011)

Article Pharmacology & Pharmacy

Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats

Kinga Burda et al.

PHARMACOLOGICAL REPORTS (2011)

Review Pharmacology & Pharmacy

Third Generation Antipsychotic Drugs: Partial Agonism or Receptor Functional Selectivity?

Richard B. Mailman et al.

CURRENT PHARMACEUTICAL DESIGN (2010)

Article Biochemical Research Methods

Taming anxiety in laboratory mice

Jane L. Hurst et al.

NATURE METHODS (2010)

Review Neurosciences

Animal models of neuropsychiatric disorders

Eric J. Nestler et al.

NATURE NEUROSCIENCE (2010)

Article Biochemistry & Molecular Biology

Dose translation from animal to human studies revisited

Shannon Reagan-Shaw et al.

FASEB JOURNAL (2008)

Article Genetics & Heredity

The involvement of ErbB4 with schizophrenia:: Association and expression studies

G Silberberg et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2006)

Article Behavioral Sciences

Food intake, water intake, and drinking spout side preference of 28 mouse strains

AA Bachmanov et al.

BEHAVIOR GENETICS (2002)

Article Multidisciplinary Sciences

Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter

RR Gainetdinov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)