4.5 Review

Corneal Crosslinking: Present and Future

Journal

ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY
Volume 11, Issue 5, Pages 441-452

Publisher

ASIA-PACIFIC ACAD OPHTHALMOLOGY-APAO
DOI: 10.1097/APO.0000000000000557

Keywords

keratoconus; cornea; crosslinking; ectatic disorders

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Corneal crosslinking (CXL) has emerged as an effective method for treating keratoconus and managing other ocular pathologies. This review summarizes the current role of CXL in keratoconus, its alternative uses, and future developments.
Keratoconus is a progressive corneal thinning disorder that can lead to vision loss. In the last 2 decades, corneal crosslinking (CXL) has emerged as an effective method to halt the progression of keratoconus and reduce the number of patients requiring keratoplasty. The procedure has been adopted globally and has evolved to become a part of combination treatments to regularize the cornea and improve visual outcomes. CXL has even been extrapolated in managing other ocular pathologies such as progressive myopia, infectious keratitis, and bullous keratopathy. This review aims to summarize the current role of CXL in keratoconus and its alternative uses, and provide insights into future developments in this fast-developing field.

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