Difference between morning and evening blood pressure at home and nocturnal hypoxia in the general practitioner-based J-HOP study

The aim of this study was to determine the independent association of nocturnal hypoxia with morning minus evening home blood pressure (MEdif) in a cohort of outpatients with at least one cardiovascular risk. A total of 1053 participants underwent home blood pressure (BP) portable pulse oximetry measurements, and 147 (14%) had an MEdif >= 20 mmHg, where MEdif was defined as the difference between morning and evening home systolic BP. When participants were divided into quartiles according to the lowest oxygen saturation (SpO(2)) during the nighttime, those in the lowest quartile (range, 54-79%) were significantly more likely to have MEdif >= 20 mmHg than those in the top quartile (range, 89-97%) (adjusted odds ratio, 1.98; 95% confidence interval, 1.13-3.49). The present study revealed an association between lowest SpO(2) during the nighttime and increased MEdif in a cohort of outpatients with at least one cardiovascular risk.

Automated summary

This study revealed an association between nocturnal hypoxia and morning minus evening home blood pressure (MEdif) in a cohort of outpatients with at least one cardiovascular risk.