Journal
NANOMATERIALS
Volume 6, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/nano6070133
Keywords
tissue engineering; nanomaterials; cardiac infarction; scaffold; patch; injectable
Categories
Funding
- California State University Long Beach's Office of Research
- Sponsored Programs Summer Student Research Assistantships Program
- California State University Sally Casanova Pre-Doctoral Program
- College of Engineering Honors Program
- California State University, Long Beach
- California State University
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Since their synthesizing introduction to the research community, nanomaterials have infiltrated almost every corner of science and engineering. Over the last decade, one such field has begun to look at using nanomaterials for beneficial applications in tissue engineering, specifically, cardiac tissue engineering. During a myocardial infarction, part of the cardiac muscle, or myocardium, is deprived of blood. Therefore, the lack of oxygen destroys cardiomyocytes, leaving dead tissue and possibly resulting in the development of arrhythmia, ventricular remodeling, and eventual heart failure. Scarred cardiac muscle results in heart failure for millions of heart attack survivors worldwide. Modern cardiac tissue engineering research has developed nanomaterial applications to combat heart failure, preserve normal heart tissue, and grow healthy myocardium around the infarcted area. This review will discuss the recent progress of nanomaterials for cardiovascular tissue engineering applications through three main nanomaterial approaches: scaffold designs, patches, and injectable materials.
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