Electric Cell-Substrate Impedance Sensing (ECIS) as a Convenient Tool to Assess the Potential of Low Molecular Fraction Derived from Medicinal Fungus Cerrena unicolor in Action on L929 and CT-26 Cell Lines

Article Biochemistry & Molecular Biology

Antiproliferative Properties of Triterpenoids by ECIS Method-A New Promising Approach in Anticancer Studies?

Anna Hordyjewska et al.

Summary: Electric cell-substrate impedance sensing was used to investigate the anticancer activities of betulin and betulinic acid. The results showed that these compounds have potential antitumor properties and little toxicity to healthy cells.

MOLECULES (2022)

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Article Biotechnology & Applied Microbiology

Chemopreventive activity of bioactive fungal fractions isolated from milk-supplemented cultures of Cerrena unicolor and Pycnoporus sanguineus on colon cancer cells

Mateusz Piet et al.

Summary: The research found that Cerrena unicolor and Pycnoporus sanguineus have anti-tumorigenic activity against colon cancer cells and exhibit anticancer properties through various mechanisms. Culturing the fungi on milk-supplemented media may improve the health benefits of both milk and mushrooms.

3 BIOTECH (2021)

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Review Biochemistry & Molecular Biology

Mushroom-Derived Bioactive Molecules as Immunotherapeutic Agents: A Review

Dinesh K. Patel et al.

Summary: Mushrooms with enhanced medicinal properties contain various bioactive compounds that provide antimicrobial, antidiabetic, antiviral, hepatoprotective, antitumor, and immunomodulatory effects. The presence of beta-glucans in mushroom cell walls plays a significant role in their biological activity. Extracting active ingredients from mushrooms for therapeutic purposes can lead to the development of functional medicinal foods.

MOLECULES (2021)

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Article Biochemistry & Molecular Biology

Pro-Health and Anti-Cancer Activity of Fungal Fractions Isolated from Milk-Supplemented Cultures of Lentinus (Pleurotus) Sajor-caju

Adrian Zajac et al.

Summary: The study demonstrates that supplementing the culture medium of Lentinus sajor-caju with cow milk enriches the nutrient composition and enhances antioxidant enzyme activity, leading to decreased levels of free radicals. Additionally, the extracts show anti-cancer properties by decreasing cancer cell viability, promoting apoptosis, and increasing nitric oxide secretion. These findings suggest that Lentinus sajor-caju has potential as a source of healthy biomolecules in modern medicine or functional foods.

BIOMOLECULES (2021)

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Review Microbiology