Antibiofilm Activity of Biocide Metal Ions Containing Bioactive Glasses (BGs): A Mini Review

One of the major clinical issues during the implantation procedure is the bacterial infections linked to biofilms. Due to their tissue localization and the type of bacteria involved, bacterial infections at implant sites are usually difficult to treat, which increases patient morbidity and even mortality. The difficulty of treating biofilm-associated infections and the emergence of multidrug-resistant bacteria are further challenges for the scientific community to develop novel biomaterials with excellent biocompatibility and antibacterial properties. Given their ability to stimulate bone formation and have antibacterial properties, metal ion-doped bioactive glasses (BGs) have received considerable research. This mini review aims to be successful in presenting the developments made about the role of biocide metal ions incorporated into BGs against the development of bacterial biofilms and the spread of nosocomial diseases.

Automated summary

Bacterial infections linked to biofilms are a major clinical issue during implantation procedures, as they are difficult to treat and can lead to patient morbidity and mortality. Developing novel biomaterials with excellent biocompatibility and antibacterial properties is a challenge due to the difficulty in treating biofilm-associated infections and the emergence of multidrug-resistant bacteria. Metal ion-doped bioactive glasses have received significant research attention for their ability to stimulate bone formation and possess antibacterial properties.