Journal
JOURNAL OF ORAL SCIENCE
Volume 58, Issue 4, Pages 569-574Publisher
NIHON UNIV, SCHOOL DENTISTRY
DOI: 10.2334/josnusd.16-0280
Keywords
chamomile; gingivitis; mouthwash
Funding
- Brazilian agency (CNPq) [471407/2009-7]
- Brazilian agency (CAPES)
- Brazilian agency (FUNCAP) [247.01.00/09]
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This pilot study evaluated the clinical efficacy of a mouthwash containing 1% Matricaria chamomilla L. (MTC) extract in reducing gingival inflammation and plaque formation in patients undergoing orthodontic treatment with fixed appliances. This randomized, double-blind, placebo-controlled study enrolled a total of 30 males and females (age, 10-40 years) with fixed orthodontic appliances and a minimum of 20 natural teeth. The participants were allocated to three groups (n = 10 each) and asked to rinse with 15 mL of a placebo, 0.12% chlorhexidine (CHX), or 1% MTC mouthwash, immediately after brushing for 1 min, in the morning and evening, for 15 days. Data (mean SD) on visible plaque index (VPI) and gingival bleeding index (GBI) were recorded on days 1 and 15. The placebo group exhibited increases in VPI and GBI (10.2% and 23.1%, respectively) from day 1 to day 15. As compared with placebo, VPI and GBI significantly decreased in the MTC group (-25.6% and 29.9%, respectively) and the CHX group (-39.9% and 32.0%, respectively). In summary, MTC reduced biofilm accumulation and gingival bleeding in patients with gingivitis, probably because of its antimicrobial and anti-inflammatory activities.
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