☆ 4.5 Article

Ultrafast PCR Detection of COVID-19 by Using a Microfluidic Chip-Based System

BIOENGINEERING-BASEL (2022)

Related references

Note: Only part of the references are listed.

Article Chemistry, Analytical

Microfluidics Temperature Compensating and Monitoring Based on Liquid Metal Heat Transfer

Jiyu Meng et al.

Summary: In this study, the relationship between microfluids and the glass substrate in microfluidic devices was investigated. With an intelligent structure design and liquid metal, temperature sensing of micro-scale fluids using a millimeter-scale industrial temperature sensor was demonstrated. The proposed heat transfer model and temperature control method showed excellent performance in temperature-sensitive experiments.

MICROMACHINES (2022)

Add to Collection

Article Biochemical Research Methods

Micro-PCR chip-based multifunctional ultrafast SARS-CoV-2 detection platform

Hao Yin et al.

Summary: In this study, a multifunctional rapid PCR platform was developed for point-of-care diagnosis of infectious diseases. The platform allows simultaneous screening, identification, and quantification of the virus, with fast and accurate results. It has been successfully applied to screening and quantifying SARS-CoV-2 in clinical samples.

LAB ON A CHIP (2022)

Add to Collection

Review Pediatrics

Laboratory diagnosis of COVID-19

Ekaterini S. Goudouris

Summary: This paper provides a non-systematic review on the laboratory diagnosis of COVID-19, highlighting the importance of different diagnostic methods such as pathogen detection, serological responses, laboratory tests, and imaging tests.

JORNAL DE PEDIATRIA (2021)

Add to Collection

Article Biochemical Research Methods

A fully automated microfluidic PCR-array system for rapid detection of multiple respiratory tract infection pathogens

Enqi Huang et al.

Summary: The Onestart system, utilizing a microfluidic chip, enables rapid and accurate detection of respiratory tract infection pathogens, with the entire analysis process completed within 1.5 hours. The system shows excellent specificity and stability in detecting pathogens.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2021)

Add to Collection

Article Medicine, Research & Experimental

Development of integrated microfluidic platform coupled with Surface-enhanced Raman Spectroscopy for diagnosis of COVID-19

Siddhita A. Jadhav et al.

Summary: The COVID-19 pandemic has highlighted the urgent need for a swift, sensitive, and inexpensive diagnostic protocol. The authors propose a new diagnostic approach based on Surface-enhanced Raman Spectroscopy (SERS) coupled with microfluidic devices to trap and identify viruses from diverse biological fluids. If successful, this approach could serve as a valuable tool for mass screening of COVID-19 and future viral pandemics.

MEDICAL HYPOTHESES (2021)

Add to Collection

Article Biophysics

A pocket-sized device automates multiplexed point-of-care RNA testing for rapid screening of infectious pathogens

Bowen Shu et al.

Summary: An ultraportable RNA amplification testing device is introduced for rapid screening of infectious pathogens, utilizing 3D-printed structural parts and off-the-shelf mechanical/electronic components. By preloading necessary reagents in a multi-channel droplet array chip, the device enables seamless integration of bacteria lysis, RNA extraction, and amplification, while providing visual readout and geometrically-multiplexed quantitative detection through an integrated wireless video camera.

BIOSENSORS & BIOELECTRONICS (2021)

Add to Collection

Article Infectious Diseases

Field evaluation of a rapid antigen test (Panbio™ COVID-19 Ag Rapid Test Device) for COVID-19 diagnosis in primary healthcare centres

Eliseo Albert et al.

Summary: The Panbio (TM) COVID-19 Ag Rapid Test Device performed well as a POC test for early diagnosis of COVID-19 in primary healthcare centres, with a specificity and sensitivity of 100% and 79.6% respectively. The negative predictive value of RAD was 99% and 97.9% under estimated prevalence of 5% and 10% respectively.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

Add to Collection

Article Biophysics

Fully integrated microfluidic devices for qualitative, quantitative and digital nucleic acids testing at point of care

Zedong Li et al.

Summary: Emerging miniaturized and equipment-free nucleic acid testing technologies are driving the development of fully integrated NAT devices at point of care (POC) to simplify operations, reduce contamination risks, and expand applications from qualitative to quantitative and digital detection signals. The review introduces existing commercial products, recent fully integrated microfluidic devices for NAT at POC, and discusses key issues and challenges in scientific research and product development, envisioning the future realization of MARCHED NAT devices.

BIOSENSORS & BIOELECTRONICS (2021)

Add to Collection

Article Chemistry, Analytical

A Rapid Digital PCR System with a Pressurized Thermal Cycler

Xuee Chen et al.

Summary: A silicon-based fast-generated static droplets array (SDA) chip was designed, along with a rapid digital polymerase chain reaction (dPCR) detection platform for easy sample loading and fluorescence monitoring. A pressurized thermal cycling device was used to prevent evaporation issues and enable successful amplification of templates at the nanoliter scale. The platform demonstrated quantitative DNA molecule detection and real-time fluorescence intensity measurement capabilities.

MICROMACHINES (2021)

Add to Collection

Review Biology

Medical imaging and computational image analysis in COVID-19 diagnosis: A review

Shahabedin Nabavi et al.

Summary: This study reviewed the characteristics of COVID-19 in medical images, explored the potential of automated artificial intelligence in COVID-19 diagnosis, and proposed the recommendation of collecting more patient imaging data to improve the performance of automated diagnostic methods.

COMPUTERS IN BIOLOGY AND MEDICINE (2021)

Add to Collection

Article Chemistry, Analytical

A digitalized isothermal nucleic acid testing platform based on a pump-free open droplet array microfluidic chip

Ping Mao et al.

Summary: In this study, a digital isothermal NAT platform was developed based on a pump-free open droplet array microfluidic chip, allowing for accurate quantification down to 1 copy per mu L of lambda DNA. When combined with a handheld fluorescent signal reader based on a smartphone, this integrated NAT platform offers a portable, robust, and low-cost tool for highly accurate NA quantitative analysis, showing great potential for POCT applications.

ANALYST (2021)

Add to Collection

Review Virology

Recent advances in the detection of respiratory virus infection in humans

Naru Zhang et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Real-time kinetics and high-resolution melt curves in single-molecule digital LAMP to differentiate and study specific and non-specific amplification

Justin C. Rolando et al.

NUCLEIC ACIDS RESEARCH (2020)

Add to Collection

Review Medicine, General & Internal

COVID-19 diagnosis and management: a comprehensive review

Giuseppe Pascarella et al.

JOURNAL OF INTERNAL MEDICINE (2020)

Add to Collection

Review Pharmacology & Pharmacy

Molecular immune pathogenesis and diagnosis of COVID-19

Xiaowei Li et al.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2020)

Add to Collection

Article Chemistry, Analytical

Capillarity self-driven DNA hydrogel sensor for visual quantification of microRNA

Hui Wang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

Add to Collection

Article Engineering, Multidisciplinary

A High-Throughput, Multi-Index Isothermal Amplification Platform for Rapid Detection of 19 Types of Common Respiratory Viruses Including SARS-CoV-2

Wanli Xing et al.

ENGINEERING (2020)

Add to Collection

Article Biochemical Research Methods

A fully portable microchip real-time polymerase chain reaction for rapid detection of pathogen

Rui Tong et al.

ELECTROPHORESIS (2019)

Add to Collection

Article Chemistry, Analytical

Point-of-care testing of various analytes by means of a one-step competitive displacement reaction and pregnancy test strips

Yu Zhang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

Add to Collection

Review Chemistry, Analytical

Simple Approaches to Minimally-Instrumented, Microfluidic-Based Point-of-Care Nucleic Acid Amplification Tests

Michael G. Mauk et al.

BIOSENSORS-BASEL (2018)

Add to Collection

Review Microbiology

A Basic Guide to Real Time PCR in Microbial Diagnostics: Definitions, Parameters, and Everything

Petr Kralik et al.

FRONTIERS IN MICROBIOLOGY (2017)

Add to Collection

Article Medicine, General & Internal

Analytical performance, agreement and user-friendliness of six point-of-care testing urine analysers for urinary tract infection in general practice

Marjolein J. C. Schot et al.

BMJ OPEN (2015)

Add to Collection

Review Infectious Diseases

Point-of-care detection of lipoarabinomannan (LAM) in urine for diagnosis of HIV-associated tuberculosis: a state of the art review

Stephen D. Lawn

BMC INFECTIOUS DISEASES (2012)

Add to Collection

Article Medical Laboratory Technology

Interrater reliability: the kappa statistic

Mary L. McHugh

BIOCHEMIA MEDICA (2012)

Add to Collection

Article Biochemical Research Methods

A lab-on-a-chip device for rapid identification of avian influenza viral RNA by solid-phase PCR

Yi Sun et al.

LAB ON A CHIP (2011)

Add to Collection

Review Chemistry, Analytical

Point-of-care testing (POCT): Current techniques and future perspectives

Peter B. Luppa et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2011)

Add to Collection

Article Engineering, Biomedical

An integrated, self-contained microfluidic cassette for isolation, amplification, and detection of nucleic acids

Dafeng Chen et al.

BIOMEDICAL MICRODEVICES (2010)

Add to Collection

Article Biochemical Research Methods

A polymer lab-on-a-chip for reverse transcription (RT)-PCR based point-of-care clinical diagnostics

Soo Hyun Lee et al.

LAB ON A CHIP (2008)

Add to Collection

Article Virology

Design and performance testing of quantitative real time PCR assays for influenza A and B viral load measurement

CL Ward et al.

JOURNAL OF CLINICAL VIROLOGY (2004)

Add to Collection

© Peeref 2019-2024. All rights reserved.