Journal
CHEMICAL COMMUNICATIONS
Volume 58, Issue 90, Pages 12576-12579Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cc05038b
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Funding
- National Natural Science Foundation of China [82030107, 21702046]
- Key Scientific Research Program of the Higher Education Institution of Henan Province [22A150005]
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In this study, BDP-Se-MOS was obtained by optimizing phenyl selenide-based BODIPYs, which showed resistance to ROS and selective detection of Cys. BDP-Se-MOS not only discriminated between different cells, but also allowed real-time imaging of Cys levels in tumor-bearing mice.
Herein, by optimizing phenyl selenide-based BODIPYs, BDP-Se-MOS was obtained, which possessed resistance to ROS and could selectively detect Cys. BDP-Se-MOS could not only discriminate between normal and cancer cells, but also image Cys levels in tumor-bearing mice in real time as well as image the fluctuations of Cys levels in an APAP-induced DILI model.
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